Awareness and practice of dentists in gulf cooperation council countries regarding medication-related osteonecrosis of the jaw – A web-based survey

Mohammad Zakaria Nassani, Bassel Tarakji, Abdulaziz Maree Alqahtani, Faisal Mehsen Alali, Mohammed Noushad, Samer Rastam, Anas B. Alsalhani, Mohammed Khalid Alfadel, Abdulaziz Abdullah Alzuabi, Abdulhaleem Muhammad Ateen, Abdullah Bahjat Khojah, Mahmud Uz Zaman, Abdullah Saad Alqahtani, Nasser Raqe Alqhtani, Abdullah Bin Nabhan, Faisal S. Alhedyan, Omar Kujan, Sadeq Ali Al-Maweri

Research output: Contribution to journalArticlepeer-review


Background/purpose: Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication among dental patients undergoing treatment with antiresorptive medications such as bisphosphonate and denosumab. The present survey investigated the awareness and practice of dentists in the Gulf Cooperation Council (GCC) countries regarding MRONJ. Materials and methods: This questionnaire-based study was conducted among dental practitioners in all six GCC countries. A questionnaire was designed and distributed among all potential participants via different social media platforms. SPSS version 22 was used for data analysis, and P-value <0.05 was considered statistically significant. Results: Overall, 1685 dentists from the six GCC countries participated in the present study. The surveyed dentists revealed relatively fair practices and awareness regarding MRONJ and its prevention, with the majority reported asking their patients about history of anti-osteoporotic medications (67.8%), recording name of the medication (73.1%) and duration of treatment (75.5%). However, the majority of the participants were unconfident about the duration of drug holiday prior to dental surgical interventions (70.6%) and the overall good level of knowledge/practice related to MRONJ was just 50.6%. The regression analysis revealed that previous exposure to MRONJ cases and attending a seminar, course, meeting, or conference about osteonecrosis of the jaw were independent predictors for positive awareness/good practice regarding MRONJ (P < 0.05). Conclusion: The results show inadequate awareness and practices of dentists practicing in GCC countries regarding MRONJ, with significant variations among the countries. Therefore, appropriate interventions such as periodic continuous education courses are required to improve dentists’ knowledge and practices regarding MRONJ.

Original languageEnglish
Pages (from-to)1677-1684
Number of pages8
JournalJournal of Dental Sciences
Issue number4
Publication statusPublished - Oct 2023


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