Asymmetries of long-latency intracortical inhibition in motor cortex and handedness

Geoff Hammond, C.L. Garvey

Research output: Contribution to journalArticle

16 Citations (Scopus)


Paired-pulse transcranial magnetic stimulation was used in three experiments to measure the properties of long-latency intracortical inhibition (LICI) acting on the relaxed first dorsal interosseus muscle of the left and right hand in right-handed volunteers. The experiments show that LICI is asymmetrical: it emerges more rapidly and is greater in the dominant than non-dominant hand shortly after activation of the LICI circuits, and is greater with low-intensity conditioning stimulus intensities in the dominant than non-dominant hand. These findings suggest that asymmetrical function of long-latency inhibitory circuits in motor cortex might contribute to the asymmetrical dexterity between the hands, possibly through their inhibitory control of the circuits responsible for short-latency inhibition.
Original languageEnglish
Pages (from-to)449-453
JournalExperimental Brain Research
Issue number4
Publication statusPublished - 2006


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