Asymmetric hydroamination and ring-opening aminationreactions catalyzed by a new family of cationic N-heterocycliccarbene iridium(I) complexes

The catalytic hydroamination represents the most straightforward way to prepare amines from simple unsaturated hydrocarbon precursors and has therefore been extensively studied in the past few decades. Intramolecular hydroamination, in which an important class of hydroamination reactions, can be extremely useful for the synthesis of biologically very important 5-, 6- and 7-membered saturated N-heterocycles. During my PhD studies, I have used different N-heterocyclic carbene (NHC) ligands and various dienes for the synthesis of unsaturated cationic NHC-iridium complexes that show very good catalytic behavior in the (enantioselective) intramolecular hydroamination and the asymmetric ring-opening amination reactions.