Association of obstructive sleep apnoea and long-term cardiovascular events in a prospective sleep clinic cohort

Bindiya Shenoy

Research output: ThesisDoctoral Thesis

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Abstract

Obstructive sleep apnoea (OSA), a complex heterogenous sleep disorder, is an independent risk factor for major adverse cardiovascular events (MACE); however, the magnitude of this relationship is not fully understood. This thesis studied a large well-characterised sleep clinic cohort, the West Australian Sleep Health Study, and sought to examine the relationship between OSA, cardiovascular risk factors, and adherent long-term continuous positive airway pressure therapy to identify OSA phenotypes at increased risk of MACE. The findings of this thesis may help facilitate a precision medicine approach in OSA and provide important targets for clinical trials of OSA treatment.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Walsh, Jen, Supervisor
  • McQuillan, Brendan, Supervisor
  • Cadby, Gemma, Supervisor
  • Singh, Bhajan, Supervisor
  • McArdle, Nigel, Supervisor
  • Eastwood, Peter, Supervisor, External person
Thesis sponsors
Award date30 May 2024
DOIs
Publication statusUnpublished - 2023

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