Assessment of short-term outcomes following unintentional ingestions of ʻʻoral contraceptive pillsʻʻ by toddlers

Ann-Maree Lynch, B. Mckay, Lindsay Murray

    Research output: Contribution to journalArticle

    Abstract

    Background. Cases of unintentional pediatric ingestions of oral contraceptive pills are commonly reported to Poison Information Centers (PICs). No study had examined clinical outcomes in the past 30 years, although the hormone content of these preparations has been substantially reduced. We assessed short-term outcomes to determine the relevance of advice provided, particularly that vaginal bleeding can occur. Methods. Prospective observational study of cases reported to a state PIC were followed up over a 5-month period. Results. There were 63 cases with complete follow-up, average age was 2 years and 10 months; 65% of the patients were female. Median number of pills ingested was 5.0 [Interquartile Range (IQR) 3–16.5]. Minor symptoms including vomiting and irritability were reported in 44% of cases. No case of vaginal bleeding was reported. Conclusion. No major clinical effects and no instances of vaginal bleeding were reported.
    Original languageEnglish
    Pages (from-to)174-177
    JournalClinical Toxicology
    Volume47
    Issue number2
    DOIs
    Publication statusPublished - 2009

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    Uterine Hemorrhage
    Poisons
    Information services
    Oral Contraceptives
    Information Centers
    Eating
    Pediatrics
    Hormones
    Vomiting
    Observational Studies
    Prospective Studies

    Cite this

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    title = "Assessment of short-term outcomes following unintentional ingestions of ʻʻoral contraceptive pillsʻʻ by toddlers",
    abstract = "Background. Cases of unintentional pediatric ingestions of oral contraceptive pills are commonly reported to Poison Information Centers (PICs). No study had examined clinical outcomes in the past 30 years, although the hormone content of these preparations has been substantially reduced. We assessed short-term outcomes to determine the relevance of advice provided, particularly that vaginal bleeding can occur. Methods. Prospective observational study of cases reported to a state PIC were followed up over a 5-month period. Results. There were 63 cases with complete follow-up, average age was 2 years and 10 months; 65{\%} of the patients were female. Median number of pills ingested was 5.0 [Interquartile Range (IQR) 3–16.5]. Minor symptoms including vomiting and irritability were reported in 44{\%} of cases. No case of vaginal bleeding was reported. Conclusion. No major clinical effects and no instances of vaginal bleeding were reported.",
    author = "Ann-Maree Lynch and B. Mckay and Lindsay Murray",
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    language = "English",
    volume = "47",
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    Assessment of short-term outcomes following unintentional ingestions of ʻʻoral contraceptive pillsʻʻ by toddlers. / Lynch, Ann-Maree; Mckay, B.; Murray, Lindsay.

    In: Clinical Toxicology, Vol. 47, No. 2, 2009, p. 174-177.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Assessment of short-term outcomes following unintentional ingestions of ʻʻoral contraceptive pillsʻʻ by toddlers

    AU - Lynch, Ann-Maree

    AU - Mckay, B.

    AU - Murray, Lindsay

    PY - 2009

    Y1 - 2009

    N2 - Background. Cases of unintentional pediatric ingestions of oral contraceptive pills are commonly reported to Poison Information Centers (PICs). No study had examined clinical outcomes in the past 30 years, although the hormone content of these preparations has been substantially reduced. We assessed short-term outcomes to determine the relevance of advice provided, particularly that vaginal bleeding can occur. Methods. Prospective observational study of cases reported to a state PIC were followed up over a 5-month period. Results. There were 63 cases with complete follow-up, average age was 2 years and 10 months; 65% of the patients were female. Median number of pills ingested was 5.0 [Interquartile Range (IQR) 3–16.5]. Minor symptoms including vomiting and irritability were reported in 44% of cases. No case of vaginal bleeding was reported. Conclusion. No major clinical effects and no instances of vaginal bleeding were reported.

    AB - Background. Cases of unintentional pediatric ingestions of oral contraceptive pills are commonly reported to Poison Information Centers (PICs). No study had examined clinical outcomes in the past 30 years, although the hormone content of these preparations has been substantially reduced. We assessed short-term outcomes to determine the relevance of advice provided, particularly that vaginal bleeding can occur. Methods. Prospective observational study of cases reported to a state PIC were followed up over a 5-month period. Results. There were 63 cases with complete follow-up, average age was 2 years and 10 months; 65% of the patients were female. Median number of pills ingested was 5.0 [Interquartile Range (IQR) 3–16.5]. Minor symptoms including vomiting and irritability were reported in 44% of cases. No case of vaginal bleeding was reported. Conclusion. No major clinical effects and no instances of vaginal bleeding were reported.

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