TY - THES
T1 - Assessment of coronary artery calcium and its associations with familial and non-familial cardiovascular risk factors
AU - Vargas Garcia, Cristian
PY - 2019
Y1 - 2019
N2 - The aim of this project was to evaluate the role of cardiac computed tomography scanning for coronary artery calcium score in the assessment of subclinical coronary atherosclerosis burden in asymptomatic subjects with familial and non-familial cardiovascular risk factors. The findings of this investigation could improve cardiovascular risk stratification of patients. Result are particularly relevant in those with familial hypercholesterolaemia, a monogenic disorder that leads to premature coronary disease. This may also be employed as a method for early identification and prompt treatment initiation, to personalise the intensity of treatment, increase the adherence to therapy, and triage further investigations.
AB - The aim of this project was to evaluate the role of cardiac computed tomography scanning for coronary artery calcium score in the assessment of subclinical coronary atherosclerosis burden in asymptomatic subjects with familial and non-familial cardiovascular risk factors. The findings of this investigation could improve cardiovascular risk stratification of patients. Result are particularly relevant in those with familial hypercholesterolaemia, a monogenic disorder that leads to premature coronary disease. This may also be employed as a method for early identification and prompt treatment initiation, to personalise the intensity of treatment, increase the adherence to therapy, and triage further investigations.
KW - Cardiovascular risk assessment
KW - Coronary artery calcium score
KW - Cardiac imaging
KW - Familial hypercholesterolaemia
KW - Cardiovascular risk factors
U2 - 10.26182/5d9eac0872854
DO - 10.26182/5d9eac0872854
M3 - Master's Thesis
ER -