Abstract
Abruptio placentae during pregnancy can result in significant morbidity and mortality to both mother and infant A comprehensive literature search of publications from 1966 to April 1995 identified fl studies on the association between maternal cocaine use and abruptio placentae. Their results were combined in a meta-analysis. The pooled odds ratio for abruptio placentae and maternal cocaine use was 3.92 (95% confidence interval 2.77-5.46). The strength and consistency of the association, its biological plausibility and the results of experimental studies in animals all suggest that cocaine use during pregnancy causes abruptio placentae.
Original language | English |
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Pages (from-to) | 1547-1551 |
Journal | Addiction |
Volume | 92 |
Issue number | 11 |
DOIs | |
Publication status | Published - 1997 |