Assessing hemispheric specialization for processing arithmetic skills in adults: A functional transcranial doppler ultrasonography (fTCD) study

Veronica M. Connaughton, Azhani Amiruddin, Karen L. Clunies-Ross, Noel French, Allison M. Fox

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background A major model of the cerebral circuits that underpin arithmetic calculation is the triple-code model of numerical processing. This model proposes that the lateralization of mathematical operations is organized across three circuits: a left-hemispheric dominant verbal code; a bilateral magnitude representation of numbers and a bilateral Arabic number code. New method This study simultaneously measured the blood flow of both middle cerebral arteries using functional transcranial Doppler ultrasonography to assess hemispheric specialization during the performance of both language and arithmetic tasks. The propositions of the triple-code model were assessed in a non-clinical adult group by measuring cerebral blood flow during the performance of multiplication and subtraction problems. Participants were 17 adults aged between 18–27 years. We obtained laterality indices for each type of mathematical operation and compared these in participants with left-hemispheric language dominance. It was hypothesized that blood flow would lateralize to the left hemisphere during the performance of multiplication operations, but would not lateralize during the performance of subtraction operations. Results Hemispheric blood flow was significantly left lateralized during the multiplication task, but was not lateralized during the subtraction task. Comparison with existing method(s) Compared to high spatial resolution neuroimaging techniques previously used to measure cerebral lateralization, functional transcranial Doppler ultrasonography is a cost-effective measure that provides a superior temporal representation of arithmetic cognition. Conclusions These results provide support for the triple-code model of arithmetic processing and offer complementary evidence that multiplication operations are processed differently in the adult brain compared to subtraction operations. © 2017 Elsevier B.V. 

Original languageEnglish
Pages (from-to)33-41
Number of pages9
JournalJournal of Neuroscience Methods
Volume283
DOIs
Publication statusPublished - 1 May 2017

Fingerprint

Cerebral Dominance
Doppler Transcranial Ultrasonography
Cerebrovascular Circulation
Language
Middle Cerebral Artery
Neuroimaging
Cognition
Costs and Cost Analysis
Brain

Cite this

@article{ed8b1dae095b47609fb11d5cb740e817,
title = "Assessing hemispheric specialization for processing arithmetic skills in adults: A functional transcranial doppler ultrasonography (fTCD) study",
abstract = "Background A major model of the cerebral circuits that underpin arithmetic calculation is the triple-code model of numerical processing. This model proposes that the lateralization of mathematical operations is organized across three circuits: a left-hemispheric dominant verbal code; a bilateral magnitude representation of numbers and a bilateral Arabic number code. New method This study simultaneously measured the blood flow of both middle cerebral arteries using functional transcranial Doppler ultrasonography to assess hemispheric specialization during the performance of both language and arithmetic tasks. The propositions of the triple-code model were assessed in a non-clinical adult group by measuring cerebral blood flow during the performance of multiplication and subtraction problems. Participants were 17 adults aged between 18–27 years. We obtained laterality indices for each type of mathematical operation and compared these in participants with left-hemispheric language dominance. It was hypothesized that blood flow would lateralize to the left hemisphere during the performance of multiplication operations, but would not lateralize during the performance of subtraction operations. Results Hemispheric blood flow was significantly left lateralized during the multiplication task, but was not lateralized during the subtraction task. Comparison with existing method(s) Compared to high spatial resolution neuroimaging techniques previously used to measure cerebral lateralization, functional transcranial Doppler ultrasonography is a cost-effective measure that provides a superior temporal representation of arithmetic cognition. Conclusions These results provide support for the triple-code model of arithmetic processing and offer complementary evidence that multiplication operations are processed differently in the adult brain compared to subtraction operations. {\circledC} 2017 Elsevier B.V. ",
keywords = "Arithmetic, Cerebral lateralization, fTCD, Functional transcranial doppler, Multiplication, Subtraction",
author = "Connaughton, {Veronica M.} and Azhani Amiruddin and Clunies-Ross, {Karen L.} and Noel French and Fox, {Allison M.}",
year = "2017",
month = "5",
day = "1",
doi = "10.1016/j.jneumeth.2017.03.010",
language = "English",
volume = "283",
pages = "33--41",
journal = "Journal of Neuroscience Methods",
issn = "0165-0270",
publisher = "Elsevier",

}

Assessing hemispheric specialization for processing arithmetic skills in adults : A functional transcranial doppler ultrasonography (fTCD) study. / Connaughton, Veronica M.; Amiruddin, Azhani; Clunies-Ross, Karen L.; French, Noel; Fox, Allison M.

In: Journal of Neuroscience Methods, Vol. 283, 01.05.2017, p. 33-41.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Assessing hemispheric specialization for processing arithmetic skills in adults

T2 - A functional transcranial doppler ultrasonography (fTCD) study

AU - Connaughton, Veronica M.

AU - Amiruddin, Azhani

AU - Clunies-Ross, Karen L.

AU - French, Noel

AU - Fox, Allison M.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Background A major model of the cerebral circuits that underpin arithmetic calculation is the triple-code model of numerical processing. This model proposes that the lateralization of mathematical operations is organized across three circuits: a left-hemispheric dominant verbal code; a bilateral magnitude representation of numbers and a bilateral Arabic number code. New method This study simultaneously measured the blood flow of both middle cerebral arteries using functional transcranial Doppler ultrasonography to assess hemispheric specialization during the performance of both language and arithmetic tasks. The propositions of the triple-code model were assessed in a non-clinical adult group by measuring cerebral blood flow during the performance of multiplication and subtraction problems. Participants were 17 adults aged between 18–27 years. We obtained laterality indices for each type of mathematical operation and compared these in participants with left-hemispheric language dominance. It was hypothesized that blood flow would lateralize to the left hemisphere during the performance of multiplication operations, but would not lateralize during the performance of subtraction operations. Results Hemispheric blood flow was significantly left lateralized during the multiplication task, but was not lateralized during the subtraction task. Comparison with existing method(s) Compared to high spatial resolution neuroimaging techniques previously used to measure cerebral lateralization, functional transcranial Doppler ultrasonography is a cost-effective measure that provides a superior temporal representation of arithmetic cognition. Conclusions These results provide support for the triple-code model of arithmetic processing and offer complementary evidence that multiplication operations are processed differently in the adult brain compared to subtraction operations. © 2017 Elsevier B.V. 

AB - Background A major model of the cerebral circuits that underpin arithmetic calculation is the triple-code model of numerical processing. This model proposes that the lateralization of mathematical operations is organized across three circuits: a left-hemispheric dominant verbal code; a bilateral magnitude representation of numbers and a bilateral Arabic number code. New method This study simultaneously measured the blood flow of both middle cerebral arteries using functional transcranial Doppler ultrasonography to assess hemispheric specialization during the performance of both language and arithmetic tasks. The propositions of the triple-code model were assessed in a non-clinical adult group by measuring cerebral blood flow during the performance of multiplication and subtraction problems. Participants were 17 adults aged between 18–27 years. We obtained laterality indices for each type of mathematical operation and compared these in participants with left-hemispheric language dominance. It was hypothesized that blood flow would lateralize to the left hemisphere during the performance of multiplication operations, but would not lateralize during the performance of subtraction operations. Results Hemispheric blood flow was significantly left lateralized during the multiplication task, but was not lateralized during the subtraction task. Comparison with existing method(s) Compared to high spatial resolution neuroimaging techniques previously used to measure cerebral lateralization, functional transcranial Doppler ultrasonography is a cost-effective measure that provides a superior temporal representation of arithmetic cognition. Conclusions These results provide support for the triple-code model of arithmetic processing and offer complementary evidence that multiplication operations are processed differently in the adult brain compared to subtraction operations. © 2017 Elsevier B.V. 

KW - Arithmetic

KW - Cerebral lateralization

KW - fTCD

KW - Functional transcranial doppler

KW - Multiplication

KW - Subtraction

UR - http://www.scopus.com/inward/record.url?scp=85016408288&partnerID=8YFLogxK

U2 - 10.1016/j.jneumeth.2017.03.010

DO - 10.1016/j.jneumeth.2017.03.010

M3 - Article

VL - 283

SP - 33

EP - 41

JO - Journal of Neuroscience Methods

JF - Journal of Neuroscience Methods

SN - 0165-0270

ER -