Appropriate antithrombotic therapy use in a hospitalised cohort of atrial fibrillation patients in Western Australia, 2009-2016: Predictors and temporal trends

Rebecca Daisy Hutchens

doi:10.26182/5cb6a2e501bb3

Appropriate antithrombotic therapy use in a hospitalised cohort of atrial fibrillation patients in Western Australia, 2009-2016: Predictors and temporal trends

Rebecca Daisy Hutchens

UWA Medical School

Research output: Thesis › Master's Thesis

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Abstract

This retrospective cohort study examines trends in antithrombotic therapy use in patients with non-valvular atrial fibrillation (AF) on discharge from hospital in Perth, Western Australia. Between 2009-2016, 11,294 index AF admissions were identified with 86.3% at high risk of stroke (CHA₂DS₂-VASc≥2 in men and 3 in women). Use of oral anticoagulation (OAC) therapy in high-risk subjects improved over the period, with substantial uptake of non-vitamin K oral anticoagulants. However, by 2016 less than half of high-risk patients received appropriate OAC therapy and elderly age and HAS-BLED risk factors remained strong barriers to OAC use.

Original language	English
Qualification	Masters
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Briffa, Tom, Supervisor Hung, Joe, Supervisor McQuillan, Brendan, Supervisor
Thesis sponsors	Australian Government Research Training Program
Award date	29 Dec 2018
DOIs	https://doi.org/10.26182/5cb6a2e501bb3
Publication status	Unpublished - 2018

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10.26182/5cb6a2e501bb3

THESIS - MASTER OF CLINICAL RESEARCH - HUTCHENS, Rebecca Daisy - 2018
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Cite this

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title = "Appropriate antithrombotic therapy use in a hospitalised cohort of atrial fibrillation patients in Western Australia, 2009-2016: Predictors and temporal trends",

abstract = "This retrospective cohort study examines trends in antithrombotic therapy use in patients with non-valvular atrial fibrillation (AF) on discharge from hospital in Perth, Western Australia. Between 2009-2016, 11,294 index AF admissions were identified with 86.3\% at high risk of stroke (CHA2DS2-VASc≥2 in men and 3 in women). Use of oral anticoagulation (OAC) therapy in high-risk subjects improved over the period, with substantial uptake of non-vitamin K oral anticoagulants. However, by 2016 less than half of high-risk patients received appropriate OAC therapy and elderly age and HAS-BLED risk factors remained strong barriers to OAC use.",

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doi = "10.26182/5cb6a2e501bb3",

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AU - Hutchens, Rebecca Daisy

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N2 - This retrospective cohort study examines trends in antithrombotic therapy use in patients with non-valvular atrial fibrillation (AF) on discharge from hospital in Perth, Western Australia. Between 2009-2016, 11,294 index AF admissions were identified with 86.3% at high risk of stroke (CHA2DS2-VASc≥2 in men and 3 in women). Use of oral anticoagulation (OAC) therapy in high-risk subjects improved over the period, with substantial uptake of non-vitamin K oral anticoagulants. However, by 2016 less than half of high-risk patients received appropriate OAC therapy and elderly age and HAS-BLED risk factors remained strong barriers to OAC use.

AB - This retrospective cohort study examines trends in antithrombotic therapy use in patients with non-valvular atrial fibrillation (AF) on discharge from hospital in Perth, Western Australia. Between 2009-2016, 11,294 index AF admissions were identified with 86.3% at high risk of stroke (CHA2DS2-VASc≥2 in men and 3 in women). Use of oral anticoagulation (OAC) therapy in high-risk subjects improved over the period, with substantial uptake of non-vitamin K oral anticoagulants. However, by 2016 less than half of high-risk patients received appropriate OAC therapy and elderly age and HAS-BLED risk factors remained strong barriers to OAC use.

KW - Atrial fibrillation

KW - Stroke prevention

KW - Anticoagulation

U2 - 10.26182/5cb6a2e501bb3

DO - 10.26182/5cb6a2e501bb3

M3 - Master's Thesis

ER -

Appropriate antithrombotic therapy use in a hospitalised cohort of atrial fibrillation patients in Western Australia, 2009-2016: Predictors and temporal trends

Abstract

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