The water-enriched mined-out area, which led to frequent accidents and the serious destruction of ecological environment and serious threat to coal-mining practices. To ensure safe mining practices and to avoid the intrusion of water from the bases of coal deposits, the detection of the mined-out areas, especially the water-filled mined-out area in advanced, is one of the most important issues. This research focuses on detecting mined-out area enriched by water with the large-loop transient electromagnetic method. Data acquisition system was arranged along 23 survey lines, and the total of 1975 survey points were recorded. An inversion technique was used to interpret the TEM data. The inversion results suggested that the mined-out areas enriched by water always exhibit a very low-resistivity, the resistivity contour present closed circle sharp. There are three main water enriched mined-out areas, named JS1, JS2, and JS3 in the north part of the survey area, as well as three main water weak-enriched areas named RJS1, RJS2 and RJS3 in the west and southwest part of the survey area can be inferred by TEM, the interpretation results were verified by drilling. Large loop TEM is proved as an efficient way to investigate water enriched mined-out areas under the rugged topography conditions, and this work provides more detailed geological information to the coal mining enterprise for further coal-mining practices safety arrangement.