Antimicrobial Drugs and Bacterial Amyloid Peptide Induce Toxic Manifestations in Chronic Diseases

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Abstract

Novel information indicates the corruption by bacterial amyloid peptide of the amyloid peripheral sink hypothesis in man. A healthy
diet and early antimicrobial drug/peptide therapy is essential to prevent toxic manifestations with relevance to bacterial amyloid peptide
induced oligomeric amyloid beta toxicity to peripheral and brain cells. In the developing world the increase in plasma LPS and bacterial
amyloid peptide needs to be carefully considered to prevent interference with cholesterol specifically involved with antimicrobial peptide
therapy. Antibiotics/antimicrobial therapy used either against bacteria or against fungus now are of concern with antibiotic resistance
expected to cost the global antibacterial market approximately 36 billion dollars by the year 2022.
Original languageEnglish
Pages1-4
Number of pages4
Volume6.1
Specialist publicationEC Pharmacology and Toxicology
Publication statusPublished - 4 Jan 2018

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