Antimalarial drugs as inspiration for herbicides

Research output: Contribution to journalArticle

Abstract

In addition to good stewardship, the unabated rise in herbicide resistance and dearth of truly new herbicides demands that new molecules be found. Over 30 years ago, a chloro-plast-like organelle was found in the malarial parasite Plas-modium falciparum and herbicides demonstrated a close relationship existed to plants. Recently this idea was turned on its head by exploiting the boom in malaria research to search for new herbicide chemistry and it provided interesting start-ing points for development. The merit of such an approach is underlined by tetflupyrolimet, the first truly novel herbicide in 30 years, and whose target has been a popular subject for antimalarial drug development for 15 years. Which other antimalarial targets, drugs and drug leads might reach across the parasite-plant divide to inspire new herbicides?.

Original languageEnglish
Pages (from-to)216-220
Number of pages5
JournalOutlooks on Pest Management
Volume31
Issue number5
DOIs
Publication statusPublished - Oct 2020

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