[Truncated] Natural medicines have become a popular alternative to conventional medications. In particular, the essential oil of Melaleuca alternifolia, also known as tea tree oil, has become accepted in the community, and increasingly by medical practitioners, as a legitimate alternative to conventional therapies. The growing acceptance of tea tree oil by healthcare professionals may be attributed in part, to the sound scientific data that has been published mainly on the antibacterial properties of the oil. Unfortunately, the antifungal properties of tea tree oil have not been thoroughly investigated. Therefore, the purpose of this thesis was to redress this imbalance and investigate the antifungal activity of tea tree oil. Studies were focused initially on determining the antifungal susceptibilities of a wide range of fungi to both tea tree oil and its components. Then further investigations were conducted to establish the mechanism of action of tea tree oil and components against fungi, in particular Candida albicans.
|Doctor of Philosophy
|Unpublished - 2002
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