Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats

Eliza James, P. Daisy, S. Ignacimuthu, V. Duraipandiyan

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

The increasing prevalence of diabetes mellitus worldwide is an issue of major socio-economic concern Diabetes mellitus is a complex and a multifarious group of disorders that disturbs the metabolism of carbohydrates, fat and protein. Medicinal plants play an important role in the management of diabetes mellitus especially in developing countries. Costus speciosus is widely used in Indian medicine to treat various diseases. Eremanthin was isolated from C speciosus. The structure was identified using gas chromatography-mass spectrometry (GC-MS) analysis. Eremanthin was administered to streptozotocin (ST-Z) (50 mg/kg bw) induced diabetic male Wistar rats at different doses (5,10,20 mg/kg bw) for 60 days. Plasma glucose level was significantly (p
Original languageEnglish
Pages (from-to)67-72
JournalChemico-Biological Interactions
Volume182
DOIs
Publication statusPublished - 2009

Fingerprint Dive into the research topics of 'Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats'. Together they form a unique fingerprint.

  • Cite this