Antibiotic use and Nuclear Receptor Inactivation linked to Mitophagy in Diabetes and Chronic Diseases

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Abstract

NAFLD is now relevant to defective antimicrobial drug
metabolism in diabetes and neurodegenerative diseases.
The NAFLD epidemic is expected by the year 2050 to
effect between 20-30% of the global population. Excessive
systemic administration of antibiotic use with NAFLD should
be avoided to prevent excessive LPS release with antibiotic
use associated with mitophagy in NAFLD and multisystem
diseases that include diabetes, neurodegenerative diseases and
soft tissue diseases such as diabetic foot ulcer.
Original languageEnglish
JournalJournal of Diabetes and Clinical Studies
Volume2
Issue number1
Publication statusPublished - 6 Nov 2018

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