An oil and water emulsion phantom for biomedical terahertz spectroscopy

C. Reid; Adam P. Gibson; J. C. Hebden; V. P. Wallace

doi:10.1109/ISSMDBS.2007.4338284

An oil and water emulsion phantom for biomedical terahertz spectroscopy

C. Reid, Adam P. Gibson, J. C. Hebden, V. P. Wallace

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

6 Citations (Scopus)

Abstract

In order to determine the ability of THz spectroscopy to analyse the composition of biological tissue, a phantom containing combinations of water and lipids was developed. Initially, the absorption coefficient and refractive index of five pure commercially available lipids was measured between 0 and 3 THz. A suitable lipid for phantom manufacture was then chosen and a series of oil-water emulsions were made using surfactants. The lipid content ranged from 0% to 100%. THz spectra of the absorption coefficient and refractive index of these emulsions were measured. Using spectral decomposition techniques based on the Beer Lambert law, the percentage of oil and water in the emulsion was determined. The results show good qualitative agreement with the known compositions. The absolute oil and water content showed a systematic error of 10%. These initial results demonstrate that THz spectroscopy has the potential to determine the composition of biological tissues

Original language	English
Title of host publication	Proceedings of the 4th IEEE-EMBS International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2007, "From Terahertz Imaging to Telehealth Technologies"
Pages	25-28
Number of pages	4
DOIs	https://doi.org/10.1109/ISSMDBS.2007.4338284
Publication status	Published - 2007
Externally published	Yes
Event	4th International Summer School and Symposium of Medical Devices and Biosensors, ISSS-MDBS 2007 - Cambridge, United Kingdom Duration: 19 Aug 2007 → 22 Aug 2007

Conference

Conference	4th International Summer School and Symposium of Medical Devices and Biosensors, ISSS-MDBS 2007
Country/Territory	United Kingdom
City	Cambridge
Period	19/08/07 → 22/08/07

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10.1109/ISSMDBS.2007.4338284

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Reid, C., Gibson, A. P., Hebden, J. C., & Wallace, V. P. (2007). An oil and water emulsion phantom for biomedical terahertz spectroscopy. In Proceedings of the 4th IEEE-EMBS International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2007, "From Terahertz Imaging to Telehealth Technologies" (pp. 25-28). Article 4338284 https://doi.org/10.1109/ISSMDBS.2007.4338284

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title = "An oil and water emulsion phantom for biomedical terahertz spectroscopy",

abstract = "In order to determine the ability of THz spectroscopy to analyse the composition of biological tissue, a phantom containing combinations of water and lipids was developed. Initially, the absorption coefficient and refractive index of five pure commercially available lipids was measured between 0 and 3 THz. A suitable lipid for phantom manufacture was then chosen and a series of oil-water emulsions were made using surfactants. The lipid content ranged from 0% to 100%. THz spectra of the absorption coefficient and refractive index of these emulsions were measured. Using spectral decomposition techniques based on the Beer Lambert law, the percentage of oil and water in the emulsion was determined. The results show good qualitative agreement with the known compositions. The absolute oil and water content showed a systematic error of 10%. These initial results demonstrate that THz spectroscopy has the potential to determine the composition of biological tissues",

author = "C. Reid and Gibson, {Adam P.} and Hebden, {J. C.} and Wallace, {V. P.}",

year = "2007",

doi = "10.1109/ISSMDBS.2007.4338284",

language = "English",

isbn = "142441346X",

pages = "25--28",

booktitle = "Proceedings of the 4th IEEE-EMBS International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2007, {"}From Terahertz Imaging to Telehealth Technologies{"}",

note = "4th International Summer School and Symposium of Medical Devices and Biosensors, ISSS-MDBS 2007 ; Conference date: 19-08-2007 Through 22-08-2007",

}

Reid, C, Gibson, AP, Hebden, JC & Wallace, VP 2007, An oil and water emulsion phantom for biomedical terahertz spectroscopy. in Proceedings of the 4th IEEE-EMBS International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2007, "From Terahertz Imaging to Telehealth Technologies"., 4338284, pp. 25-28, 4th International Summer School and Symposium of Medical Devices and Biosensors, ISSS-MDBS 2007, Cambridge, United Kingdom, 19/08/07. https://doi.org/10.1109/ISSMDBS.2007.4338284

An oil and water emulsion phantom for biomedical terahertz spectroscopy. / Reid, C.; Gibson, Adam P.; Hebden, J. C. et al.
Proceedings of the 4th IEEE-EMBS International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2007, "From Terahertz Imaging to Telehealth Technologies". 2007. p. 25-28 4338284.

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

TY - GEN

T1 - An oil and water emulsion phantom for biomedical terahertz spectroscopy

AU - Reid, C.

AU - Gibson, Adam P.

AU - Hebden, J. C.

AU - Wallace, V. P.

PY - 2007

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N2 - In order to determine the ability of THz spectroscopy to analyse the composition of biological tissue, a phantom containing combinations of water and lipids was developed. Initially, the absorption coefficient and refractive index of five pure commercially available lipids was measured between 0 and 3 THz. A suitable lipid for phantom manufacture was then chosen and a series of oil-water emulsions were made using surfactants. The lipid content ranged from 0% to 100%. THz spectra of the absorption coefficient and refractive index of these emulsions were measured. Using spectral decomposition techniques based on the Beer Lambert law, the percentage of oil and water in the emulsion was determined. The results show good qualitative agreement with the known compositions. The absolute oil and water content showed a systematic error of 10%. These initial results demonstrate that THz spectroscopy has the potential to determine the composition of biological tissues

AB - In order to determine the ability of THz spectroscopy to analyse the composition of biological tissue, a phantom containing combinations of water and lipids was developed. Initially, the absorption coefficient and refractive index of five pure commercially available lipids was measured between 0 and 3 THz. A suitable lipid for phantom manufacture was then chosen and a series of oil-water emulsions were made using surfactants. The lipid content ranged from 0% to 100%. THz spectra of the absorption coefficient and refractive index of these emulsions were measured. Using spectral decomposition techniques based on the Beer Lambert law, the percentage of oil and water in the emulsion was determined. The results show good qualitative agreement with the known compositions. The absolute oil and water content showed a systematic error of 10%. These initial results demonstrate that THz spectroscopy has the potential to determine the composition of biological tissues

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SN - 9781424413461

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BT - Proceedings of the 4th IEEE-EMBS International Summer School and Symposium on Medical Devices and Biosensors, ISSS-MDBS 2007, "From Terahertz Imaging to Telehealth Technologies"

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Y2 - 19 August 2007 through 22 August 2007

ER -

An oil and water emulsion phantom for biomedical terahertz spectroscopy

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