An objective and reproducible method for quantification of aortic regurgitation after TAVI

Carl Schultz, T.L.B. Slots, G. Yong, J.P.M.M. Aben, N.M. Van Mieghem, M.J. Swaans, Z. Rahhab, N. El Faquir, R.J.V. Van Geuns, G.E.G. Mast, F. Zijlstra, P.P.T. De Jaegere

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    Abstract

    Aims: We describe a new semi-automated method that measures aortic regurgitation (AR) on contrast aortography with the objectives of reducing the inter-observer variability and standardising image acquisition. Methods and results: Aortograms from three participating centres were reviewed to generate the following quality criteria: entire left ventricle and aortic root in view, descending aorta or TOE probe not over-projected, breath hold, no table motion, and adequate contrast opacification of the aortic root. AR was visually graded (Sellers) and was quantified by measuring the area under time-contrast density curves in the aortic root (reference) and the left ventricle. Quality criteria were met in 44 retrospectively identified aortograms and in 22 (69%) of 32 prospectively collected aortograms. The visual AR grade (Sellers) was highly correlated with time-density measurements including relative area under the curve (RAUC) and qRA index (r=0.81 and 0.83, respectively, p
    Original languageEnglish
    Pages (from-to)355-363
    JournalEuroIntervention
    Volume10
    Issue number3
    DOIs
    Publication statusPublished - 2014

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    Schultz, C., Slots, T. L. B., Yong, G., Aben, J. P. M. M., Van Mieghem, N. M., Swaans, M. J., Rahhab, Z., El Faquir, N., Van Geuns, R. J. V., Mast, G. E. G., Zijlstra, F., & De Jaegere, P. P. T. (2014). An objective and reproducible method for quantification of aortic regurgitation after TAVI. EuroIntervention, 10(3), 355-363. https://doi.org/10.4244/EIJY14M05_06