An investigation of the relationships of umbilical cord blood androgen and estrogen levels to autistic-like traits and verbal and nonverbal abilities

Esha Jamnadass

Research output: ThesisDoctoral Thesis

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Abstract

This thesis examined biologically active estrogen and androgen composite levels in umbilical cord blood at birth and investigated their relationship to autistic-like traits, verbal, visuospatial and nonverbal abilities in a population cohort and a high-risk infant sibling cohort. Sex steroid levels were not significantly related to autistic-like traits or verbal, nonverbal or visuospatial abilities. There findings do not support the extreme male brain theory, but do not invalidate existing findings. Future research should consider other factors that may influence this relationship including sex differences in outcome measures, developmental time periods of sampling and genetic and biological factors (e.g. androgen receptors).
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Thesis sponsors
Award date25 May 2020
DOIs
Publication statusUnpublished - 2020

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