An investigation of the impact of variations of DVH calculation algorithms on DVH dependant radiation therapy plan evaluation metrics

A.M. Kennedy, J.A. Lane, Martin Ebert

    Research output: Chapter in Book/Conference paperConference paperpeer-review

    5 Citations (Scopus)

    Abstract

    Plan review systems often allow dose volume histogram (DVH) recalculation as part of a quality assurance process for trials. A review of the algorithms provided by a number of systems indicated that they are often very similar. One notable point of variation between implementations is in the location and frequency of dose sampling. This study explored the impact such variations can have on DVH based plan evaluation metrics (Normal Tissue Complication Probability (NTCP), min, mean and max dose), for a plan with small structures placed over areas of high dose gradient. Dose grids considered were exported from the original planning system at a range of resolutions. We found that for the CT based resolutions used in all but one plan review systems (CT and CT with guaranteed minimum number of sampling voxels in the x and y direction) results were very similar and changed in a similar manner with changes in the dose grid resolution despite the extreme conditions. Differences became noticeable however when resolution was increased in the axial (z) direction. Evaluation metrics also varied differently with changing dose grid for CT based resolutions compared to dose grid based resolutions. This suggests that if DVHs are being compared between systems that use a different basis for selecting sampling resolution it may become important to confirm that a similar resolution was used during calculation. © Published under licence by IOP Publishing Ltd.
    Original languageEnglish
    Title of host publicationJournal of Physics: Conference Series
    Place of PublicationBristol, UK
    PublisherInstitute of Physics
    Pages012093 (5 pages)
    Volume489
    DOIs
    Publication statusPublished - 2014
    Event17th International Conference on the Use of Computers in Radiation Therapy - Melbourne, Australia
    Duration: 6 May 20139 May 2013

    Conference

    Conference17th International Conference on the Use of Computers in Radiation Therapy
    Country/TerritoryAustralia
    CityMelbourne
    Period6/05/139/05/13

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