An introduction to clinical trial design

A. Schultz; B. R. Saville; J. A. Marsh; T. L. Snelling

doi:10.1016/j.prrv.2019.06.002

An introduction to clinical trial design

A. Schultz, B. R. Saville, J. A. Marsh, T. L. Snelling

Research output: Contribution to journal › Review article

1 Citation (Scopus)

Abstract

Clinicians and other decision makers in healthcare use results from clinical trials to inform practice. Interpretation of clinical trial results can be challenging, as weaknesses in trial design, data collection, analysis or reporting, can compromise the usefulness of results. A good working knowledge of clinical trial design is essential to expertly interpret and determine the validity and generalizability of the results. This manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches. The focus will be on confirmatory clinical trials.

Original language	English
Journal	Paediatric Respiratory Reviews
DOIs	https://doi.org/10.1016/j.prrv.2019.06.002
Publication status	Published - 26 Jun 2019

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10.1016/j.prrv.2019.06.002

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1 Curtailed
1 Finished
1 Active

LCTRC - BEAT-CF: Bayesian Evidence-Adaptive Trial to Optimise Management of Cystic Fibrosis
Snelling, T., Berry, S., Jaffé, A., Marsh, J., McKenzie, A., Ranganathan, S., Schultz, A. & Stick, S.
Medical Research Future Fund MRFF
1/01/18 → 31/05/23
Project: Research
Ensuring optimal treatment for Aboriginal children with chronic wet cough
Schultz, A.
National Health & Medical Research Council NHMRC
1/01/19 → 31/12/20
Project: Research
Comparative effectiveness research in childhood infections to improve decision-making in health policy and clinical practice
Snelling, T.
National Health & Medical Research Council NHMRC
1/01/16 → 20/10/17
Project: Research

Cite this

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An introduction to clinical trial design

Abstract

Access to Document

LCTRC - BEAT-CF: Bayesian Evidence-Adaptive Trial to Optimise Management of Cystic Fibrosis

Ensuring optimal treatment for Aboriginal children with chronic wet cough

Comparative effectiveness research in childhood infections to improve decision-making in health policy and clinical practice

Cite this