TY - JOUR
T1 - An In Vivo Perspective of the Role(s) of the Alternative Oxidase Pathway
AU - Del-Saz, Néstor Fernández
AU - Ribas-Carbo, Miquel
AU - McDonald, Allison E.
AU - Lambers, Hans
AU - Fernie, Alisdair R.
AU - Florez-Sarasa, Igor
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Despite intense research on the in vitro characterization of regulatory factors modulating the alternative oxidase (AOX) pathway, the regulation of its activity in vivo is still not fully understood. Advances concerning in vivo regulation of AOX based on the oxygen-isotope fractionation technique are reviewed, and regulatory factors that merit future research are highlighted. In addition, we review and discuss the main biological functions assigned to the plant AOX, and suggest future experiments involving in vivo activity measurements to test different hypothesized physiological roles.
AB - Despite intense research on the in vitro characterization of regulatory factors modulating the alternative oxidase (AOX) pathway, the regulation of its activity in vivo is still not fully understood. Advances concerning in vivo regulation of AOX based on the oxygen-isotope fractionation technique are reviewed, and regulatory factors that merit future research are highlighted. In addition, we review and discuss the main biological functions assigned to the plant AOX, and suggest future experiments involving in vivo activity measurements to test different hypothesized physiological roles.
KW - alternative oxidase
KW - in vivo regulation
KW - metabolic flexibility
KW - oxygen-isotope fractionation
KW - respiration
UR - http://www.scopus.com/inward/record.url?scp=85038348670&partnerID=8YFLogxK
U2 - 10.1016/j.tplants.2017.11.006
DO - 10.1016/j.tplants.2017.11.006
M3 - Review article
C2 - 29269217
AN - SCOPUS:85038348670
SN - 1360-1385
VL - 23
SP - 206
EP - 219
JO - Trends in Plant Science
JF - Trends in Plant Science
IS - 3
ER -