Abstract
Although the normal histology of anogenital mammary-like glands (AGMLG) has been studied, no systemic investigation has been performed on the immunoprofile of these structures. We studied intact AGMLG with a broad panel of antibodies. The immunoprofile of AGMLG is similar to that of a normal breast tissue, and there are similarities to eccrine glands and coils about cytokeratin expression. Our immunohistochemical data may contribute to understanding of the pathogenesis of lesions arising from AGMLG.
| Original language | English |
|---|---|
| Pages (from-to) | 599-605 |
| Number of pages | 7 |
| Journal | American Journal of Dermatopathology |
| Volume | 39 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - Aug 2017 |
Cite this
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An Immunohistochemical Study of Anogenital Mammary-Like Glands. / Konstantinova, Anastasia M.; Stewart, Colin J. R.; Kyrpychova, Liubov; Belousova, Irena E.; Michal, Michal; Kazakov, Dmitry V.
In: American Journal of Dermatopathology, Vol. 39, No. 8, 08.2017, p. 599-605.Research output: Contribution to journal › Article
TY - JOUR
T1 - An Immunohistochemical Study of Anogenital Mammary-Like Glands
AU - Konstantinova, Anastasia M.
AU - Stewart, Colin J. R.
AU - Kyrpychova, Liubov
AU - Belousova, Irena E.
AU - Michal, Michal
AU - Kazakov, Dmitry V.
PY - 2017/8
Y1 - 2017/8
N2 - Although the normal histology of anogenital mammary-like glands (AGMLG) has been studied, no systemic investigation has been performed on the immunoprofile of these structures. We studied intact AGMLG with a broad panel of antibodies. The immunoprofile of AGMLG is similar to that of a normal breast tissue, and there are similarities to eccrine glands and coils about cytokeratin expression. Our immunohistochemical data may contribute to understanding of the pathogenesis of lesions arising from AGMLG.
AB - Although the normal histology of anogenital mammary-like glands (AGMLG) has been studied, no systemic investigation has been performed on the immunoprofile of these structures. We studied intact AGMLG with a broad panel of antibodies. The immunoprofile of AGMLG is similar to that of a normal breast tissue, and there are similarities to eccrine glands and coils about cytokeratin expression. Our immunohistochemical data may contribute to understanding of the pathogenesis of lesions arising from AGMLG.
KW - anogenital mammary-like glands
KW - immunohistochemistry
KW - vulva
KW - steroid receptors
KW - myoepithelial cells
KW - PSEUDOANGIOMATOUS STROMAL HYPERPLASIA
KW - CARCINOMA IN-SITU
KW - MYOEPITHELIAL CELL LINEAGES
KW - EXTRAMAMMARY PAGET-DISEASE
KW - MULTINUCLEATED GIANT-CELLS
KW - HIDRADENOMA-PAPILLIFERUM
KW - DUCTAL CARCINOMA
KW - BREAST CARCINOMAS
KW - AGGRESSIVE PHENOTYPE
KW - NEOPLASTIC TISSUES
U2 - 10.1097/DAD.0000000000000724
DO - 10.1097/DAD.0000000000000724
M3 - Article
VL - 39
SP - 599
EP - 605
JO - The American Journal of dermatopathology
JF - The American Journal of dermatopathology
SN - 0193-1091
IS - 8
ER -