An alternative synthesis of some carbohydrate α-amino acids

G.S. Forman; Adrian Scaffidi; Robert Stick

doi:10.1071/CH03214

An alternative synthesis of some carbohydrate α-amino acids

G.S. Forman, Adrian Scaffidi, Robert Stick

School of Molecular Sciences

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Several carbohydrate ketones have been converted into their trichloromethyl-branched tertiary alcohols. A subsequent treatment of these alcohols under Corey-Link conditions (base, sodium azide, methanol) has given rise to alpha-azido esters, transformable into azido acids, amino esters, and amino acids. An amino ester and an azido acid have been coupled to form a dipeptide.

Original language	English
Pages (from-to)	25-28
Journal	Australian Journal of Chemistry
Volume	57
Issue number	1
DOIs	https://doi.org/10.1071/CH03214
Publication status	Published - 2004

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10.1071/CH03214

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abstract = "Several carbohydrate ketones have been converted into their trichloromethyl-branched tertiary alcohols. A subsequent treatment of these alcohols under Corey-Link conditions (base, sodium azide, methanol) has given rise to alpha-azido esters, transformable into azido acids, amino esters, and amino acids. An amino ester and an azido acid have been coupled to form a dipeptide.",

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AB - Several carbohydrate ketones have been converted into their trichloromethyl-branched tertiary alcohols. A subsequent treatment of these alcohols under Corey-Link conditions (base, sodium azide, methanol) has given rise to alpha-azido esters, transformable into azido acids, amino esters, and amino acids. An amino ester and an azido acid have been coupled to form a dipeptide.

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DO - 10.1071/CH03214

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JO - Australian Journal of Chemistry

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An alternative synthesis of some carbohydrate α-amino acids

Abstract

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