TY - JOUR
T1 - An Air-Stable Nickel(0) Phosphite Precatalyst for Primary Alkylamine C-N Cross-Coupling Reactions
AU - Kampmann, Sven
AU - Skelton, Brian
AU - Wild, Duncan
AU - Koutsantonis, George
AU - Stewart, Scott
PY - 2015
Y1 - 2015
N2 - Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. In this report we describe the design and preparation of a new air-stable nickel phosphite based catalyst for unique C-N bond forming processes. Specifically, (BINAP)Ni[P(OPh)3]2, is presented as an effective catalyst for a range of amination reactions between aryl halides and primary alkylamines. The results are supported by relevant kinetic studies, DFT calculations and a catalytic cycle indicating possible reaction intermediates. The amination reaction between a series of aryl halides and primary alkylamines is described using a new air-stable nickel phosphite based catalyst (BINAP)Ni[P(OPh)3]2.
AB - Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. In this report we describe the design and preparation of a new air-stable nickel phosphite based catalyst for unique C-N bond forming processes. Specifically, (BINAP)Ni[P(OPh)3]2, is presented as an effective catalyst for a range of amination reactions between aryl halides and primary alkylamines. The results are supported by relevant kinetic studies, DFT calculations and a catalytic cycle indicating possible reaction intermediates. The amination reaction between a series of aryl halides and primary alkylamines is described using a new air-stable nickel phosphite based catalyst (BINAP)Ni[P(OPh)3]2.
U2 - 10.1002/ejoc.201500734
DO - 10.1002/ejoc.201500734
M3 - Article
SN - 1434-193X
VL - 2015
SP - 5995
EP - 6004
JO - European Journal of Organic Chemistry
JF - European Journal of Organic Chemistry
IS - 27
ER -