In bridging the gap between the laboratory and the patient it is essential to consider the differences in the environment the cells are exposed to in order optimize their performance and achieve the goal of expedient wound closure. Successful delivery systems for keratinocytes to the wound bed must consider the viability and proliferation potential of the cells with protection to achieve a mature epithelial layer. The delivery systems are described in two groups, direct delivery or with the use of carrier. The clinical use of pre-confluent keratinocytes has been widely reported to be effective in augmenting wound healing.
|Title of host publication||Biomaterials for Treating Skin Loss|
|Subtitle of host publication||A volume in Woodhead Publishing Series in Biomaterials|
|Number of pages||9|
|Publication status||Published - 1 Jan 2009|