Alcohol and oral cancer

Omar Kujan, Abdulhameed Husain, Camile Farah

Research output: Chapter in Book/Conference paperChapter

3 Citations (Scopus)

Abstract

Alcohol consumption has long been recognised as one of the major risk factors for the development of oral cancer [1]. The establishment of the sole effect of alcohol on the oral mucosa and its link to the development of oral cancer have been considered a significant challenge, principally because alcohol consumption histories are difficult to verify, alter over time, both with respect to beverage type and quantity, and are frequently confounded by tobacco use [2]. This is further explained by the established joint effect of alcohol and tobacco in the development of head and neck cancers [2]. In addition, it can be difficult to obtain reliable information from patients about their alcohol intake where the data on alcohol ingestion is based on a highly subjective estimate provided by patients, and this can be due to the different drinking behaviours, e.g. some may ‘binge’ drink and others have a high daily intake. This chapter will discuss the epidemiological evidence for the role of alcohol in oral cancer, the topical and systemic effects of alcohol, alcohol-related oral carcinogenesis and the association between alcohol-containing mouthwashes and oral cancer risk. It will also outline the health benefits of alcohol moderation and cessation and its role in prevention of human oral cancer.
Original languageEnglish
Title of host publicationDevelopment of oral cancer
Subtitle of host publicationrisk factors and prevention strategies
EditorsAla-Eddin Al Moustafa
PublisherSpringer Publishing
Pages61-82
Number of pages22
ISBN (Electronic)9783319480541
ISBN (Print)9783319480534
DOIs
Publication statusPublished - 2017

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