Alcohol consumption has long been recognised as one of the major risk factors for the development of oral cancer . The establishment of the sole effect of alcohol on the oral mucosa and its link to the development of oral cancer have been considered a significant challenge, principally because alcohol consumption histories are difficult to verify, alter over time, both with respect to beverage type and quantity, and are frequently confounded by tobacco use . This is further explained by the established joint effect of alcohol and tobacco in the development of head and neck cancers . In addition, it can be difficult to obtain reliable information from patients about their alcohol intake where the data on alcohol ingestion is based on a highly subjective estimate provided by patients, and this can be due to the different drinking behaviours, e.g. some may ‘binge’ drink and others have a high daily intake. This chapter will discuss the epidemiological evidence for the role of alcohol in oral cancer, the topical and systemic effects of alcohol, alcohol-related oral carcinogenesis and the association between alcohol-containing mouthwashes and oral cancer risk. It will also outline the health benefits of alcohol moderation and cessation and its role in prevention of human oral cancer.
|Title of host publication||Development of oral cancer|
|Subtitle of host publication||risk factors and prevention strategies|
|Editors||Ala-Eddin Al Moustafa|
|Number of pages||22|
|Publication status||Published - 2017|