Age, weight and decompression sickness in rats

Peter L. Buzzacott; M. Theron; A. Mazur; Q. Wang; K. Lambrechts; I. Eftedal; S.B. B. Ardestani; F. Guerrero

doi:10.3109/13813455.2016.1140787

Age, weight and decompression sickness in rats

Peter L. Buzzacott, M. Theron, A. Mazur, Q. Wang, K. Lambrechts, I. Eftedal, S.B. B. Ardestani, F. Guerrero

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight. © 2015 Taylor and Francis.

Original language	English
Pages (from-to)	67-69
Number of pages	3
Journal	Archives of Physiology and Biochemistry
Volume	122
Issue number	2
DOIs	https://doi.org/10.3109/13813455.2016.1140787
Publication status	Published - 14 Mar 2016

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10.3109/13813455.2016.1140787

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title = "Age, weight and decompression sickness in rats",

abstract = "Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight. {\textcopyright} 2015 Taylor and Francis.",

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TY - JOUR

T1 - Age, weight and decompression sickness in rats

AU - Buzzacott, Peter L.

AU - Theron, M.

AU - Mazur, A.

AU - Wang, Q.

AU - Lambrechts, K.

AU - Eftedal, I.

AU - Ardestani, S.B. B.

AU - Guerrero, F.

PY - 2016/3/14

Y1 - 2016/3/14

N2 - Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight. © 2015 Taylor and Francis.

AB - Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight. © 2015 Taylor and Francis.

U2 - 10.3109/13813455.2016.1140787

DO - 10.3109/13813455.2016.1140787

M3 - Article

SN - 1381-3455

VL - 122

SP - 67

EP - 69

JO - Archives of Physiology and Biochemistry

JF - Archives of Physiology and Biochemistry

IS - 2

ER -

Age, weight and decompression sickness in rats

Abstract

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