Abstract
Skin integrity is essential for normal physiological function. The capacity to regenerate is overwhelmed and integrity of the cutaneous surface is restored by scarring. The limited capacity to heal by regeneration and the sequel of scarring has driven the exploration of techniques for expedient wound treatment to restore the cutaneous barrier in a regenerative pattern.
The development of the systems of cell isolation, proliferation, and delivery now provide a range of therapeutic options for cell-based therapies into clinical practice. The clinical outcome of the technologies is now widely reported in the literature with improved understanding of their impact on cutaneous healing. The clinical use needs to consider the patient's needs, the availability of the technology, the risk–benefit analysis, and the cost–benefit analysis.
Tissue engineering of skin for skin repair has progressed remarkably in the recent decades with the future of healing by regeneration, a challenging but realistic goal.
The development of the systems of cell isolation, proliferation, and delivery now provide a range of therapeutic options for cell-based therapies into clinical practice. The clinical outcome of the technologies is now widely reported in the literature with improved understanding of their impact on cutaneous healing. The clinical use needs to consider the patient's needs, the availability of the technology, the risk–benefit analysis, and the cost–benefit analysis.
Tissue engineering of skin for skin repair has progressed remarkably in the recent decades with the future of healing by regeneration, a challenging but realistic goal.
| Original language | English |
|---|---|
| Title of host publication | Skin tissue Engineering and Regeneration Medicine |
| Editors | Mohammad Z. Albanna , James H. Holmes IV |
| Publisher | Academic Press |
| Pages | 299-315 |
| Number of pages | 17 |
| ISBN (Print) | 9780128016541 |
| DOIs | |
| Publication status | Published - 2016 |