Advances in Biomarkers and Insulin Therapy with Relevance to Reversal of Diabetes

Ian Martins

Research output: Contribution to specialist publicationEditorialpeer-review

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Abstract

Identification of biomarker tests in diabetes to assess Sirt 1 repression linked to autoimmune disease and mitophagy has become of critical importance to the expected diabetes pandemic connected to various organ diseases. Plasma Sirt 1 analysis with other biomarkers are essential to determine autoimmune disease connected to mitophagy and the reversal of Type 2/Type 3 diabetes. Insulin therapy to prevent hyperglycemia now requires Sirt 1 expression to determine mitochondrial function and insulin secretion with relevance to programmed cell death in obesity, diabetes and neurodegenerative diseases. Diet, temperature regulation and insulin therapy may improve Sirt 1 levels connected to the prevention of primary autoimmune disease in the pancreas (insulin secretion), adipose tissue, liver and brain.
Original languageEnglish
Pages9-14
Number of pages6
Volume1
No.1
Specialist publicationJournal of Studies on Diabetes
Publication statusPublished - 20 Jun 2018

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