TY - JOUR
T1 - Adult body size, sexual history and adolescent sexual development, may predict risk of developing prostate cancer
T2 - Results from the New South Wales Lifestyle and Evaluation of Risk Study (CLEAR)
AU - Nair-Shalliker, Visalini
AU - Yap, Sarsha
AU - Nunez, Carlos
AU - Egger, Sam
AU - Rodger, Jennifer
AU - Patel, Manish I.
AU - O'Connell, Dianne L.
AU - Sitas, Freddy
AU - Armstrong, Bruce K.
AU - Smith, David P.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - Prostate cancer (PC) is the most common non-cutaneous cancer in men worldwide. The relationships between PC and possible risk factors for PC cases (n = 1,181) and male controls (n = 875) from the New South Wales (NSW) Cancer, Lifestyle and Evaluation of Risk Study (CLEAR) were examined in this study. The associations between PC risk and paternal history of PC, body mass index (BMI), medical conditions, sexual behaviour, balding pattern and puberty, after adjusting for age, income, region of birth, place of residence, and PSA testing, were examined. Adjusted risk of PC was higher for men with a paternal history of PC (OR = 2.31; 95%CI: 1.70–3.14), personal history of prostatitis (OR = 2.30; 95%CI: 1.44–3.70), benign prostatic hyperplasia (OR = 2.29; 95%CI: 1.79–2.93), being overweight (vs. normal; OR = 1.24; 95%CI: 0.99–1.55) or obese (vs. normal; OR = 1.44; 95%CI: 1.09–1.89), having reported more than seven sexual partners in a lifetime (vs.
AB - Prostate cancer (PC) is the most common non-cutaneous cancer in men worldwide. The relationships between PC and possible risk factors for PC cases (n = 1,181) and male controls (n = 875) from the New South Wales (NSW) Cancer, Lifestyle and Evaluation of Risk Study (CLEAR) were examined in this study. The associations between PC risk and paternal history of PC, body mass index (BMI), medical conditions, sexual behaviour, balding pattern and puberty, after adjusting for age, income, region of birth, place of residence, and PSA testing, were examined. Adjusted risk of PC was higher for men with a paternal history of PC (OR = 2.31; 95%CI: 1.70–3.14), personal history of prostatitis (OR = 2.30; 95%CI: 1.44–3.70), benign prostatic hyperplasia (OR = 2.29; 95%CI: 1.79–2.93), being overweight (vs. normal; OR = 1.24; 95%CI: 0.99–1.55) or obese (vs. normal; OR = 1.44; 95%CI: 1.09–1.89), having reported more than seven sexual partners in a lifetime (vs.
KW - balding
KW - obesity
KW - Prostate cancer
KW - puberty
KW - sexual activity
UR - http://www.scopus.com/inward/record.url?scp=84998706914&partnerID=8YFLogxK
U2 - 10.1002/ijc.30471
DO - 10.1002/ijc.30471
M3 - Article
C2 - 27741552
AN - SCOPUS:84998706914
SN - 0020-7136
VL - 140
SP - 565
EP - 574
JO - International Journal of Cancer
JF - International Journal of Cancer
IS - 3
ER -
