Adaptation to heat and water shortage in large, arid-zone mammals

Although laboratory studies of large mammals have revealed valuable information on thermoregulation, such studies cannot predict accurately how animals respond in their natural habitats. Through insights obtained on ther-moregulatory behavior, body temperature variability, and selective brain cooling in free-living mammals, we show here how we can better understand the physiological capacity of large mammals to cope with hotter and drier arid-zone habitats likely with climate change. © 2014 Int. Union Physiol. Sci./Am. Physiol. Soc.