Acute kidney injury in Indigenous Australians in the Kimberley: age distribution and associated diagnoses

Joseph Mohan, David Atkinson, Emma Griffiths, Johan Rosman

Research output: Contribution to journalArticle

Abstract

OBJECTIVE:
To describe the frequencies of acute kidney injury (AKI) and of associated diagnoses in Indigenous people in a remote Western Australian region.

DESIGN:
Retrospective population-based study of AKI events confirmed by changes in serum creatinine levels.

SETTING, PARTICIPANTS:
Aboriginal and Torres Strait Islander residents of the Kimberley region of Western Australia, aged 15 years or more and without end-stage kidney disease, for whom AKI between 1 June 2009 and 30 May 2016 was confirmed by an acute rise in serum creatinine levels.

MAIN OUTCOME MEASURES:
Age-specific AKI rates; principal and other diagnoses.

RESULTS:
324 AKI events in 260 individuals were recorded; the median age of patients was 51.8 years (IQR, 43.9-61.0 years), and 176 events (54%) were in men. The overall AKI rate was 323 events (95% CI, 281-367) per 100 000 population; 92 events (28%) were in people aged 15-44 years. 52% of principal diagnoses were infectious in nature, including pneumonia (12% of events), infections of the skin and subcutaneous tissue (10%), and urinary tract infections (7.7%). 80 events (34%) were detected on or before the date of admission; fewer than one-third of discharge summaries (61 events, 28%) listed AKI as a primary or other diagnosis.

CONCLUSION:
The age distribution of AKI events among Indigenous Australians in the Kimberley was skewed to younger groups than in the national data on AKI. Infectious conditions were common in patients, underscoring the significance of environmental determinants of health. Primary care services can play an important role in preventing community-acquired AKI; applying pathology-based criteria could improve the detection of AKI.
Original languageEnglish
Number of pages5
JournalThe Medical journal of Australia
DOIs
Publication statusE-pub ahead of print - 12 Mar 2019

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Age Distribution
Acute Kidney Injury
Creatinine
Western Australia
Environmental Health
Subcutaneous Tissue
Serum
Urinary Tract Infections
Population
Chronic Kidney Failure
Primary Health Care
Pneumonia
Pathology
Skin

Cite this

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title = "Acute kidney injury in Indigenous Australians in the Kimberley: age distribution and associated diagnoses",
abstract = "OBJECTIVE:To describe the frequencies of acute kidney injury (AKI) and of associated diagnoses in Indigenous people in a remote Western Australian region.DESIGN:Retrospective population-based study of AKI events confirmed by changes in serum creatinine levels.SETTING, PARTICIPANTS:Aboriginal and Torres Strait Islander residents of the Kimberley region of Western Australia, aged 15 years or more and without end-stage kidney disease, for whom AKI between 1 June 2009 and 30 May 2016 was confirmed by an acute rise in serum creatinine levels.MAIN OUTCOME MEASURES:Age-specific AKI rates; principal and other diagnoses.RESULTS:324 AKI events in 260 individuals were recorded; the median age of patients was 51.8 years (IQR, 43.9-61.0 years), and 176 events (54{\%}) were in men. The overall AKI rate was 323 events (95{\%} CI, 281-367) per 100 000 population; 92 events (28{\%}) were in people aged 15-44 years. 52{\%} of principal diagnoses were infectious in nature, including pneumonia (12{\%} of events), infections of the skin and subcutaneous tissue (10{\%}), and urinary tract infections (7.7{\%}). 80 events (34{\%}) were detected on or before the date of admission; fewer than one-third of discharge summaries (61 events, 28{\%}) listed AKI as a primary or other diagnosis.CONCLUSION:The age distribution of AKI events among Indigenous Australians in the Kimberley was skewed to younger groups than in the national data on AKI. Infectious conditions were common in patients, underscoring the significance of environmental determinants of health. Primary care services can play an important role in preventing community-acquired AKI; applying pathology-based criteria could improve the detection of AKI.",
keywords = "Infectious diseases; Kidney diseases; Public health; Renal insufficiency; Rural health services; Skin diseases, infectious",
author = "Joseph Mohan and David Atkinson and Emma Griffiths and Johan Rosman",
year = "2019",
month = "3",
day = "12",
doi = "10.5694/mja2.50061",
language = "English",
journal = "Medical Journal Australia",
issn = "0025-729X",
publisher = "Australasian Medical Publishing Co. Ltd",

}

TY - JOUR

T1 - Acute kidney injury in Indigenous Australians in the Kimberley

T2 - age distribution and associated diagnoses

AU - Mohan, Joseph

AU - Atkinson, David

AU - Griffiths, Emma

AU - Rosman, Johan

PY - 2019/3/12

Y1 - 2019/3/12

N2 - OBJECTIVE:To describe the frequencies of acute kidney injury (AKI) and of associated diagnoses in Indigenous people in a remote Western Australian region.DESIGN:Retrospective population-based study of AKI events confirmed by changes in serum creatinine levels.SETTING, PARTICIPANTS:Aboriginal and Torres Strait Islander residents of the Kimberley region of Western Australia, aged 15 years or more and without end-stage kidney disease, for whom AKI between 1 June 2009 and 30 May 2016 was confirmed by an acute rise in serum creatinine levels.MAIN OUTCOME MEASURES:Age-specific AKI rates; principal and other diagnoses.RESULTS:324 AKI events in 260 individuals were recorded; the median age of patients was 51.8 years (IQR, 43.9-61.0 years), and 176 events (54%) were in men. The overall AKI rate was 323 events (95% CI, 281-367) per 100 000 population; 92 events (28%) were in people aged 15-44 years. 52% of principal diagnoses were infectious in nature, including pneumonia (12% of events), infections of the skin and subcutaneous tissue (10%), and urinary tract infections (7.7%). 80 events (34%) were detected on or before the date of admission; fewer than one-third of discharge summaries (61 events, 28%) listed AKI as a primary or other diagnosis.CONCLUSION:The age distribution of AKI events among Indigenous Australians in the Kimberley was skewed to younger groups than in the national data on AKI. Infectious conditions were common in patients, underscoring the significance of environmental determinants of health. Primary care services can play an important role in preventing community-acquired AKI; applying pathology-based criteria could improve the detection of AKI.

AB - OBJECTIVE:To describe the frequencies of acute kidney injury (AKI) and of associated diagnoses in Indigenous people in a remote Western Australian region.DESIGN:Retrospective population-based study of AKI events confirmed by changes in serum creatinine levels.SETTING, PARTICIPANTS:Aboriginal and Torres Strait Islander residents of the Kimberley region of Western Australia, aged 15 years or more and without end-stage kidney disease, for whom AKI between 1 June 2009 and 30 May 2016 was confirmed by an acute rise in serum creatinine levels.MAIN OUTCOME MEASURES:Age-specific AKI rates; principal and other diagnoses.RESULTS:324 AKI events in 260 individuals were recorded; the median age of patients was 51.8 years (IQR, 43.9-61.0 years), and 176 events (54%) were in men. The overall AKI rate was 323 events (95% CI, 281-367) per 100 000 population; 92 events (28%) were in people aged 15-44 years. 52% of principal diagnoses were infectious in nature, including pneumonia (12% of events), infections of the skin and subcutaneous tissue (10%), and urinary tract infections (7.7%). 80 events (34%) were detected on or before the date of admission; fewer than one-third of discharge summaries (61 events, 28%) listed AKI as a primary or other diagnosis.CONCLUSION:The age distribution of AKI events among Indigenous Australians in the Kimberley was skewed to younger groups than in the national data on AKI. Infectious conditions were common in patients, underscoring the significance of environmental determinants of health. Primary care services can play an important role in preventing community-acquired AKI; applying pathology-based criteria could improve the detection of AKI.

KW - Infectious diseases; Kidney diseases; Public health; Renal insufficiency; Rural health services; Skin diseases, infectious

U2 - 10.5694/mja2.50061

DO - 10.5694/mja2.50061

M3 - Article

JO - Medical Journal Australia

JF - Medical Journal Australia

SN - 0025-729X

ER -