Acid-base regulation as a function of body temperature in ectothermic toads, a heliothermic lizard, and a heterothermic mammal

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Abstract

1. 1.|Blood pH of an active amphibian (Bufo valliceps) and a dormant amphibian (Scaphiopus couchii) at different body temperatures was found to resemble the pH-temperature relationship for water. Their pH-temperature coefficients were -0.030 and -0.028 u/°C respectively. The blood pH of a heliothermic lizard (Dipsosaurus dorsalis) and a heterothermic mammal (Perognathus longimembris) had a lower temperature coefficient, -0.007 and -0.0085 u/°C respectively. Blood pCO2 of the amphibia, reptile and mammal decreased at low body temperatures, in conformance with the pH regime; the lizard and mammal were, however, acidotic relative to the amphibia, at low temperatures. 2. 2.|Data from the present study, and other studies, suggest that the manner in which vertebrates regulate in vivo pH at different body temperatures is quite variable, and that behavioural/physiological thermoregulators tend to have low temperature-pH coefficients. 3. 3.|The temperature-pH optimum for a tricarboxylic acid cycle enzyme, malate dehydrogenase, from P. longimembris) was about -0.008 u/°C, which corresponds closely for the temperature-pH coefficient for blood (-0.0085 u/°C). 4. 4.|The pattern of in vivo pH-temperature regulation observed in vertebrates would appear to be intimately correlated with the physico-chemical requirements for the maintenance of cellular metabolism. Neither the temperature-pH coefficient for in vivo pH regulation, or for optimal enzyme activity, necessarily parallel the observed temperature dependence of the pH of water. © 1978.
Original languageEnglish
Pages (from-to)163-171
Number of pages9
JournalJournal of Thermal Biology
Volume3
Issue number3
DOIs
Publication statusPublished - 1978

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Mammals
Lizards
toads
Body Temperature
Anura
body temperature
lizards
mammals
Acids
acids
Temperature
temperature
Amphibians
Blood
blood pH
Amphibia
amphibians
Vertebrates
vertebrates
Perognathus

Cite this

@article{d4afd989fe40431593890aa84eb6b388,
title = "Acid-base regulation as a function of body temperature in ectothermic toads, a heliothermic lizard, and a heterothermic mammal",
abstract = "1. 1.|Blood pH of an active amphibian (Bufo valliceps) and a dormant amphibian (Scaphiopus couchii) at different body temperatures was found to resemble the pH-temperature relationship for water. Their pH-temperature coefficients were -0.030 and -0.028 u/°C respectively. The blood pH of a heliothermic lizard (Dipsosaurus dorsalis) and a heterothermic mammal (Perognathus longimembris) had a lower temperature coefficient, -0.007 and -0.0085 u/°C respectively. Blood pCO2 of the amphibia, reptile and mammal decreased at low body temperatures, in conformance with the pH regime; the lizard and mammal were, however, acidotic relative to the amphibia, at low temperatures. 2. 2.|Data from the present study, and other studies, suggest that the manner in which vertebrates regulate in vivo pH at different body temperatures is quite variable, and that behavioural/physiological thermoregulators tend to have low temperature-pH coefficients. 3. 3.|The temperature-pH optimum for a tricarboxylic acid cycle enzyme, malate dehydrogenase, from P. longimembris) was about -0.008 u/°C, which corresponds closely for the temperature-pH coefficient for blood (-0.0085 u/°C). 4. 4.|The pattern of in vivo pH-temperature regulation observed in vertebrates would appear to be intimately correlated with the physico-chemical requirements for the maintenance of cellular metabolism. Neither the temperature-pH coefficient for in vivo pH regulation, or for optimal enzyme activity, necessarily parallel the observed temperature dependence of the pH of water. {\circledC} 1978.",
keywords = "acid-base heterotherm metabolism respiration temperature",
author = "Withers, {P. C.}",
year = "1978",
doi = "10.1016/0306-4565(78)90013-x",
language = "English",
volume = "3",
pages = "163--171",
journal = "Journal of Thermal Biology",
issn = "0306-4565",
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TY - JOUR

T1 - Acid-base regulation as a function of body temperature in ectothermic toads, a heliothermic lizard, and a heterothermic mammal

AU - Withers, P. C.

PY - 1978

Y1 - 1978

N2 - 1. 1.|Blood pH of an active amphibian (Bufo valliceps) and a dormant amphibian (Scaphiopus couchii) at different body temperatures was found to resemble the pH-temperature relationship for water. Their pH-temperature coefficients were -0.030 and -0.028 u/°C respectively. The blood pH of a heliothermic lizard (Dipsosaurus dorsalis) and a heterothermic mammal (Perognathus longimembris) had a lower temperature coefficient, -0.007 and -0.0085 u/°C respectively. Blood pCO2 of the amphibia, reptile and mammal decreased at low body temperatures, in conformance with the pH regime; the lizard and mammal were, however, acidotic relative to the amphibia, at low temperatures. 2. 2.|Data from the present study, and other studies, suggest that the manner in which vertebrates regulate in vivo pH at different body temperatures is quite variable, and that behavioural/physiological thermoregulators tend to have low temperature-pH coefficients. 3. 3.|The temperature-pH optimum for a tricarboxylic acid cycle enzyme, malate dehydrogenase, from P. longimembris) was about -0.008 u/°C, which corresponds closely for the temperature-pH coefficient for blood (-0.0085 u/°C). 4. 4.|The pattern of in vivo pH-temperature regulation observed in vertebrates would appear to be intimately correlated with the physico-chemical requirements for the maintenance of cellular metabolism. Neither the temperature-pH coefficient for in vivo pH regulation, or for optimal enzyme activity, necessarily parallel the observed temperature dependence of the pH of water. © 1978.

AB - 1. 1.|Blood pH of an active amphibian (Bufo valliceps) and a dormant amphibian (Scaphiopus couchii) at different body temperatures was found to resemble the pH-temperature relationship for water. Their pH-temperature coefficients were -0.030 and -0.028 u/°C respectively. The blood pH of a heliothermic lizard (Dipsosaurus dorsalis) and a heterothermic mammal (Perognathus longimembris) had a lower temperature coefficient, -0.007 and -0.0085 u/°C respectively. Blood pCO2 of the amphibia, reptile and mammal decreased at low body temperatures, in conformance with the pH regime; the lizard and mammal were, however, acidotic relative to the amphibia, at low temperatures. 2. 2.|Data from the present study, and other studies, suggest that the manner in which vertebrates regulate in vivo pH at different body temperatures is quite variable, and that behavioural/physiological thermoregulators tend to have low temperature-pH coefficients. 3. 3.|The temperature-pH optimum for a tricarboxylic acid cycle enzyme, malate dehydrogenase, from P. longimembris) was about -0.008 u/°C, which corresponds closely for the temperature-pH coefficient for blood (-0.0085 u/°C). 4. 4.|The pattern of in vivo pH-temperature regulation observed in vertebrates would appear to be intimately correlated with the physico-chemical requirements for the maintenance of cellular metabolism. Neither the temperature-pH coefficient for in vivo pH regulation, or for optimal enzyme activity, necessarily parallel the observed temperature dependence of the pH of water. © 1978.

KW - acid-base heterotherm metabolism respiration temperature

U2 - 10.1016/0306-4565(78)90013-x

DO - 10.1016/0306-4565(78)90013-x

M3 - Article

VL - 3

SP - 163

EP - 171

JO - Journal of Thermal Biology

JF - Journal of Thermal Biology

SN - 0306-4565

IS - 3

ER -