Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children

Mark P. Nicol, Lesley Workman, Margaretha Prins, Lindy Bateman, Yonas Ghebrekristos, Silindile Mbhele, Claudia M. Denkinger, Heather J. Zar

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Abstract

We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.

Original languageEnglish
Pages (from-to)E261-E263
Number of pages3
JournalPediatric Infectious Disease Journal
Volume37
Issue number10
DOIs
Publication statusPublished - Oct 2018
Externally publishedYes

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