Aberrant tonotopic organization in the inner ear damaged by kanamycin

D. Robertson, B. M. Johnstone

    Research output: Contribution to journalArticle

    59 Citations (Scopus)

    Abstract

    Spiral ganglion cell recordings were obtained from normal and kanamycin-damaged guinea pig cochleas. Results show that kanamycin poisoning, which causes loss of outer hair cells, leads to a loss of sharp, sensitive tuning and, in addition, a shift to lower frequencies in the tuning curves from a damaged region. The normal tonoptic pattern of organization is therefore greatly disrupted in the damaged cochleas.

    Original languageEnglish
    Pages (from-to)466-469
    Number of pages4
    JournalJournal of the Acoustical Society of America
    Volume66
    Issue number2
    DOIs
    Publication statusPublished - 1 Jan 1979

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