A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome

K.J. Moise; K. Dorman; G. Lamvu; G.R. Saade; N.M. Fisk; Jan Dickinson; R.D. Wilson; A. Gagnon; A. Belfort; R.O. O'Shaughnessy; U. Chitkara; S.S. Hassan; A. Sciscione; D. Skupski; Anthony Johnson

doi:10.1016/j.ajog.2005.11.007

A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome

K.J. Moise, K. Dorman, G. Lamvu, G.R. Saade, N.M. Fisk, Jan Dickinson, R.D. Wilson, A. Gagnon, A. Belfort, R.O. O'Shaughnessy, U. Chitkara, S.S. Hassan, A. Sciscione, D. Skupski, Anthony Johnson

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Abstract

ObjectiveLeft untreated, severe twin-to-twin transfusion syndrome (TTTS) presenting in the early second trimester of pregnancy is often associated with significant maternal morbidity and almost universal perinatal loss. Removal of excessive amounts of amniotic fluid through serial amniocenteses (amnioreduction) has been the mainstay of therapy. We sought to compare amnioreduction to intentional perforation of the intervening twin membrane (septostomy).

Original language	English
Pages (from-to)	701-707
Journal	American Journal of Obstetrics and Gynecology
Volume	193
Issue number	3
DOIs	https://doi.org/10.1016/j.ajog.2005.11.007
Publication status	Published - 2005

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Moise, K. J., Dorman, K., Lamvu, G., Saade, G. R., Fisk, N. M., Dickinson, J., Wilson, R. D., Gagnon, A., Belfort, A., O'Shaughnessy, R. O., Chitkara, U., Hassan, S. S., Sciscione, A., Skupski, D., & Johnson, A. (2005). A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome. American Journal of Obstetrics and Gynecology, 193(3), 701-707. https://doi.org/10.1016/j.ajog.2005.11.007

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title = "A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome",

abstract = "ObjectiveLeft untreated, severe twin-to-twin transfusion syndrome (TTTS) presenting in the early second trimester of pregnancy is often associated with significant maternal morbidity and almost universal perinatal loss. Removal of excessive amounts of amniotic fluid through serial amniocenteses (amnioreduction) has been the mainstay of therapy. We sought to compare amnioreduction to intentional perforation of the intervening twin membrane (septostomy).",

author = "K.J. Moise and K. Dorman and G. Lamvu and G.R. Saade and N.M. Fisk and Jan Dickinson and R.D. Wilson and A. Gagnon and A. Belfort and R.O. O'Shaughnessy and U. Chitkara and S.S. Hassan and A. Sciscione and D. Skupski and Anthony Johnson",

year = "2005",

doi = "10.1016/j.ajog.2005.11.007",

language = "English",

volume = "193",

pages = "701--707",

journal = "American Journal of Obstetrics & Gynecology",

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Moise, KJ, Dorman, K, Lamvu, G, Saade, GR, Fisk, NM, Dickinson, J, Wilson, RD, Gagnon, A, Belfort, A, O'Shaughnessy, RO, Chitkara, U, Hassan, SS, Sciscione, A, Skupski, D & Johnson, A 2005, 'A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome', American Journal of Obstetrics and Gynecology, vol. 193, no. 3, pp. 701-707. https://doi.org/10.1016/j.ajog.2005.11.007

TY - JOUR

T1 - A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome

AU - Moise, K.J.

AU - Dorman, K.

AU - Lamvu, G.

AU - Saade, G.R.

AU - Fisk, N.M.

AU - Dickinson, Jan

AU - Wilson, R.D.

AU - Gagnon, A.

AU - Belfort, A.

AU - O'Shaughnessy, R.O.

AU - Chitkara, U.

AU - Hassan, S.S.

AU - Sciscione, A.

AU - Skupski, D.

AU - Johnson, Anthony

PY - 2005

Y1 - 2005

N2 - ObjectiveLeft untreated, severe twin-to-twin transfusion syndrome (TTTS) presenting in the early second trimester of pregnancy is often associated with significant maternal morbidity and almost universal perinatal loss. Removal of excessive amounts of amniotic fluid through serial amniocenteses (amnioreduction) has been the mainstay of therapy. We sought to compare amnioreduction to intentional perforation of the intervening twin membrane (septostomy).

AB - ObjectiveLeft untreated, severe twin-to-twin transfusion syndrome (TTTS) presenting in the early second trimester of pregnancy is often associated with significant maternal morbidity and almost universal perinatal loss. Removal of excessive amounts of amniotic fluid through serial amniocenteses (amnioreduction) has been the mainstay of therapy. We sought to compare amnioreduction to intentional perforation of the intervening twin membrane (septostomy).

U2 - 10.1016/j.ajog.2005.11.007

DO - 10.1016/j.ajog.2005.11.007

M3 - Article

VL - 193

SP - 701

EP - 707

JO - American Journal of Obstetrics & Gynecology

JF - American Journal of Obstetrics & Gynecology

SN - 0002-9378

IS - 3

ER -

A randomized trial of amnioreduction versus septostomy in the treatment of twin-twin transfusion syndrome

Abstract

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