A Population-Based Matched-Sibling Analysis Estimating the Associations Between First Interpregnancy Interval and Birth Outcomes

Annette K. Regan, Stephen J. Ball, Joshua L. Warren, Eva Malacova, Amy Padula, Cicely Marston, Natasha Nassar, Fiona Stanley, Helen Leonard, Nicholas de Klerk, Gavin Pereira

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9 Citations (Scopus)


The association between a single interpregnancy interval (IPI) and birth outcomes has not yet been explored using matched methods. We modeled the odds of preterm birth, being small for gestational age, and having low birth weight in a second, live-born infant in a cohort of 192,041 sibling pairs born in Western Australia between 1980 and 2010. The association between IPI and birth outcomes was estimated from the interaction between birth order and IPI (with 18-23 months as the reference category), using conditional logistic regression. Matched analysis showed the odds of preterm birth were higher for siblings born following an IPI of

Original languageEnglish
Pages (from-to)9-16
Number of pages8
JournalAmerican Journal of Epidemiology
Issue number1
Publication statusPublished - Jan 2019

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