A point mutation in the ubiquitin-associated domain of SQSMT1 is sufficient to cause a Paget's disease-like disorder in mice

Medicine and Dentistry

• Autophagosome 20%
• Autophagy 40%
• Bone Architecture 40%
• Bone Disease 40%
• Bone Lesion 20%
• Bone Turnover 20%
• Codon 20%
• Diseases 20%
• Homozygote 20%
• In Vitro 20%
• Lesion 60%
• Leucine 20%
• Light Chain 20%
• Lower Limb 20%
• Ossification 20%
• Osteoclast 100%
• Osteoclast Differentiation Factor 20%
• Osteolysis 20%
• Paget Bone Disease 100%
• Paget's Disease 20%
• Point Mutation 20%
• Precursor 40%
• Proline 20%
• Protein 20%
• Ubiquitin 20%

Biochemistry, Genetics and Molecular Biology

• Autophagosome 20%
• Autophagy 40%
• Bafilomycin 20%
• Bone Turnover 20%
• Codon 20%
• Homozygote 20%
• Leucine 20%
• Light Chain 20%
• Mouse Mutant 60%
• Mutation 80%
• Nested Gene 40%
• Ossification 20%
• Osteoclast 100%
• Osteolysis 20%
• Point Mutation 20%
• Precursor 40%
• Proline 20%
• RANKL 20%
• Ubiquitin 20%
• Wild Type 60%

Agricultural and Biological Sciences

• Autophagosome 20%
• Autophagy 40%
• Bafilomycin 20%
• Bone Formation 20%
• Bone Resorption 20%
• Codon 20%
• Leucine 20%
• Mutation 80%
• Nuclear Inclusions 20%
• Osteoclast 100%
• Point Mutation 20%
• Proline 20%
• Proteins 20%
• RANKL 20%
• Ubiquitin 20%