A novel topical therapy for resistant and early peristomal pyoderma gangrenosum

Wendy A. Pearson, David A. Prentice, Deborah L. Sinclair, Lee Y. Lim, Keryln J. Carville

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Peristomal pyoderma gangrenosum (PPG) is an under-recognised and difficult condition to treat. We describe a case series using a novel topical combination therapy that promotes wound healing and allows for adhesion of the stoma appliance. A crushed oral prednisolone tablet mixed with Stomahesive Protective Powder (ConvaTec) was applied topically to seven patients with PPG and resulted in pain relief and wound healing in six of seven patients. Only one patient experienced recurrence. The novel topical therapy we describe is cost-effective, readily available, and easily applied in any inpatient or outpatient setting.

Original languageEnglish
Pages (from-to)1136-1143
Number of pages8
JournalInternational Wound Journal
Issue number5
Early online date12 Jul 2019
Publication statusPublished - 1 Oct 2019


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