The multilevel boost converter (MBC) has been widely adopted in the dc microgrid systems due to its high voltage gain and simple structure. In recent years, the power electronic loads, which usually behave as constant power loads (CPLs), are penetrating in microgrids. The incremental negative impedance of CPLs degrades the stability of microgrid systems. To ensure effective power flow and guarantee system stability, eliminating the undesired effects of CPLs is a necessity. In this article, a novel assorted nonlinear stabilizer, which is integrated with an extended nonlinear disturbance observer (NDO) and an adaptive backstepping controller, is proposed for stabilizing the MBC-fed microgrid system with CPLs. First, the reduced-order MBC model is transformed into the Brunovsky's canonical form using the exact feedback linearization technique. Second, owing to the NDO, fast system dynamic responses are achieved. Using the estimations of NDO, an adaptive backstepping controller is developed to strictly guarantee the microgrid bus voltage stability in the sense of a large signal. Simulation and experiment results are presented to verify the effectiveness and feasibility of the proposed stabilizer.