A neuropsychological profile of off-diet adults with phenylketonuria

J.J. Moyle, Allison Fox, M. Bynevelt, M. Arthur, J.R. Burnett

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The metabolic disorder phenylketonuria (PKU) is treated early by a low-phenylalanine diet. While this prevents global cognitive impairment, some patients still experience cognitive and neurophysiological abnormalities. Neuropsychological testing of early treated, currently off-diet, PKU patients attending an adult PKU clinic showed a reduction in the Perceptual Organization Index (POI), Processing Speed Index ( PSI) from the Wechsler Adult Intelligence Scale Third Edition (WAIS-III), and Part A of the Trail Making Test for the PKU group relative to controls. Taken together, these results supported a profile of reduced information-processing speed.
Original languageEnglish
Pages (from-to)436-441
JournalJournal of Clinical and Experimental Neuropsychology
Volume29
Issue number4
DOIs
Publication statusPublished - 2007

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Phenylketonurias
Diet
Trail Making Test
Phenylalanine
Intelligence
Automatic Data Processing

Cite this

Moyle, J.J. ; Fox, Allison ; Bynevelt, M. ; Arthur, M. ; Burnett, J.R. / A neuropsychological profile of off-diet adults with phenylketonuria. In: Journal of Clinical and Experimental Neuropsychology. 2007 ; Vol. 29, No. 4. pp. 436-441.
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A neuropsychological profile of off-diet adults with phenylketonuria. / Moyle, J.J.; Fox, Allison; Bynevelt, M.; Arthur, M.; Burnett, J.R.

In: Journal of Clinical and Experimental Neuropsychology, Vol. 29, No. 4, 2007, p. 436-441.

Research output: Contribution to journalArticle

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