A mitochondria–paraspeckle crosstalk

Archa H. Fox

doi:10.1038/s41556-018-0207-z

A mitochondria–paraspeckle crosstalk

Archa H. Fox

Research output: Contribution to journal › Editorial

1 Citation (Scopus)

Abstract

Paraspeckles are nuclear bodies built on the long noncoding RNA, NEAT1, that regulate cellular homeostasis, but how they sense and help under stress is unclear. A study now shows mitochondrial stress modulates paraspeckles by altering NEAT1 expression with a feedback loop that influences mitochondrial homeostasis.

Original language	English
Pages (from-to)	1108-1109
Number of pages	2
Journal	Nature Cell Biology
Volume	20
Issue number	10
DOIs	https://doi.org/10.1038/s41556-018-0207-z
Publication status	Published - 1 Oct 2018

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title = "A mitochondria–paraspeckle crosstalk",

abstract = "Paraspeckles are nuclear bodies built on the long noncoding RNA, NEAT1, that regulate cellular homeostasis, but how they sense and help under stress is unclear. A study now shows mitochondrial stress modulates paraspeckles by altering NEAT1 expression with a feedback loop that influences mitochondrial homeostasis.",

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AB - Paraspeckles are nuclear bodies built on the long noncoding RNA, NEAT1, that regulate cellular homeostasis, but how they sense and help under stress is unclear. A study now shows mitochondrial stress modulates paraspeckles by altering NEAT1 expression with a feedback loop that influences mitochondrial homeostasis.

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A mitochondria–paraspeckle crosstalk

Abstract

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