Abstract
Paraspeckles are nuclear bodies built on the long noncoding RNA, NEAT1, that regulate cellular homeostasis, but how they sense and help under stress is unclear. A study now shows mitochondrial stress modulates paraspeckles by altering NEAT1 expression with a feedback loop that influences mitochondrial homeostasis.
| Original language | English |
|---|---|
| Pages (from-to) | 1108-1109 |
| Number of pages | 2 |
| Journal | Nature Cell Biology |
| Volume | 20 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 1 Oct 2018 |
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A mitochondria–paraspeckle crosstalk. / Fox, Archa H.
In: Nature Cell Biology, Vol. 20, No. 10, 01.10.2018, p. 1108-1109.Research output: Contribution to journal › Editorial
TY - JOUR
T1 - A mitochondria–paraspeckle crosstalk
AU - Fox, Archa H.
PY - 2018/10/1
Y1 - 2018/10/1
N2 - Paraspeckles are nuclear bodies built on the long noncoding RNA, NEAT1, that regulate cellular homeostasis, but how they sense and help under stress is unclear. A study now shows mitochondrial stress modulates paraspeckles by altering NEAT1 expression with a feedback loop that influences mitochondrial homeostasis.
AB - Paraspeckles are nuclear bodies built on the long noncoding RNA, NEAT1, that regulate cellular homeostasis, but how they sense and help under stress is unclear. A study now shows mitochondrial stress modulates paraspeckles by altering NEAT1 expression with a feedback loop that influences mitochondrial homeostasis.
UR - http://www.scopus.com/inward/record.url?scp=85053845019&partnerID=8YFLogxK
U2 - 10.1038/s41556-018-0207-z
DO - 10.1038/s41556-018-0207-z
M3 - Editorial
VL - 20
SP - 1108
EP - 1109
JO - Nature Cell Biology
JF - Nature Cell Biology
SN - 1465-7392
IS - 10
ER -