A linkage group with FRA16B (the fragile site at 16q22.1)

J. Mulley, V. J. Hyland, A. Fratini, L. J. Bates, A. K. Gedeon, G. R. Sutherland

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Polymorphic DNA markers located in bands 16q13, 16q21 and 16q22 were examined for recombination with FRA16B, the fragile site at 16q22.100. A tight linkage cluster D16S10-FRA16B-D16S4-HP was established. There were no recombinants {Mathematical expression} between D16S10 and D16S4, which flank FRA16B. The markers D16S10 and D16S4 are in close proximity on the genetic map and delineate a small chromosomal segment, which contains the distamycin A-inducible fragile site.

Original languageEnglish
Pages (from-to)131-133
Number of pages3
JournalHuman Genetics
Issue number2
Publication statusPublished - 1 May 1989
Externally publishedYes


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