A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age

H. Ahsan; J. Halpern; M.G. Kibriya; B.L. Pierce; L. Tong; E. Gamazon; V. Mcguire; A. Felberg; J. Shi; F. Jasmine; S. Roy; R. Brutus; M. Argos; S. Melkonian; J. Chang-Claude; I. Andrulis; J.L. Hopper; E.M. John; K. Malone; G. Ursin; M.D. Gammon; D.C. Thomas; D. Seminara; G. Casey; J.A. Knight; M.C. Southey; G.G. Giles; R.M. Santella; E. Lee; D. Conti; D. Duggan; S. Gallinger; R. Haile; M. Jenkins; N.M. Lindor; P. Newcomb; K. Michailidou; C. Apicella; D.J. Park; J. Peto; O. Fletcher; I.D.S. Silva; M. Lathrop; D.J. Hunter; S.J. Chanock; A. Meindl; R.K. Schmutzler; B. Müller-Myhsok; M. Lochmann; L. Beckmann; R. Hein; E. Makalic; D.F. Schmidt; Q.M. Bui; Jennifer Stone; D. Flesch-Janys; N. Dahmen; H. Nevanlinna; K. Aittomäki; C. Blomqvist; P. Hall; K. Czene; A. Irwanto; J. Liu; N. Rahman; C. Turnbull; A.M. Dunning; P. Pharoah; Q. Waisfisz; H. Meijers-Heijboer; A.G. Uitterlinden; F. Rivadeneira; D. Nicolae; D.F. Easton; N.J. Cox; A.S. Whittemore

doi:10.1158/1055-9965.EPI-13-0340

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age

H. Ahsan, J. Halpern, M.G. Kibriya, B.L. Pierce, L. Tong, E. Gamazon, V. Mcguire, A. Felberg, J. Shi, F. Jasmine, S. Roy, R. Brutus, M. Argos, S. Melkonian, J. Chang-Claude, I. Andrulis, J.L. Hopper, E.M. John, K. Malone, G. UrsinM.D. Gammon, D.C. Thomas, D. Seminara, G. Casey, J.A. Knight, M.C. Southey, G.G. Giles, R.M. Santella, E. Lee, D. Conti, D. Duggan, S. Gallinger, R. Haile, M. Jenkins, N.M. Lindor, P. Newcomb, K. Michailidou, C. Apicella, D.J. Park, J. Peto, O. Fletcher, I.D.S. Silva, M. Lathrop, D.J. Hunter, S.J. Chanock, A. Meindl, R.K. Schmutzler, B. Müller-Myhsok, M. Lochmann, L. Beckmann, R. Hein, E. Makalic, D.F. Schmidt, Q.M. Bui, Jennifer Stone, D. Flesch-Janys, N. Dahmen, H. Nevanlinna, K. Aittomäki, C. Blomqvist, P. Hall, K. Czene, A. Irwanto, J. Liu, N. Rahman, C. Turnbull, A.M. Dunning, P. Pharoah, Q. Waisfisz, H. Meijers-Heijboer, A.G. Uitterlinden, F. Rivadeneira, D. Nicolae, D.F. Easton, N.J. Cox, A.S. Whittemore

Centre for Genetic Origins of Health and Diseases

Research output: Contribution to journal › Article › peer-review

65 Citations (Scopus)

Original language	English
Pages (from-to)	658-669
Journal	Cancer Epidemiology Biomarkers and Prevention
Volume	23
Issue number	4
DOIs	https://doi.org/10.1158/1055-9965.EPI-13-0340
Publication status	Published - 2014

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10.1158/1055-9965.EPI-13-0340

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Ahsan, H., Halpern, J., Kibriya, M. G., Pierce, B. L., Tong, L., Gamazon, E., Mcguire, V., Felberg, A., Shi, J., Jasmine, F., Roy, S., Brutus, R., Argos, M., Melkonian, S., Chang-Claude, J., Andrulis, I., Hopper, J. L., John, E. M., Malone, K., ... Whittemore, A. S. (2014). A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiology Biomarkers and Prevention, 23(4), 658-669. https://doi.org/10.1158/1055-9965.EPI-13-0340

Ahsan, H. ; Halpern, J. ; Kibriya, M.G. ; Pierce, B.L. ; Tong, L. ; Gamazon, E. ; Mcguire, V. ; Felberg, A. ; Shi, J. ; Jasmine, F. ; Roy, S. ; Brutus, R. ; Argos, M. ; Melkonian, S. ; Chang-Claude, J. ; Andrulis, I. ; Hopper, J.L. ; John, E.M. ; Malone, K. ; Ursin, G. ; Gammon, M.D. ; Thomas, D.C. ; Seminara, D. ; Casey, G. ; Knight, J.A. ; Southey, M.C. ; Giles, G.G. ; Santella, R.M. ; Lee, E. ; Conti, D. ; Duggan, D. ; Gallinger, S. ; Haile, R. ; Jenkins, M. ; Lindor, N.M. ; Newcomb, P. ; Michailidou, K. ; Apicella, C. ; Park, D.J. ; Peto, J. ; Fletcher, O. ; Silva, I.D.S. ; Lathrop, M. ; Hunter, D.J. ; Chanock, S.J. ; Meindl, A. ; Schmutzler, R.K. ; Müller-Myhsok, B. ; Lochmann, M. ; Beckmann, L. ; Hein, R. ; Makalic, E. ; Schmidt, D.F. ; Bui, Q.M. ; Stone, Jennifer ; Flesch-Janys, D. ; Dahmen, N. ; Nevanlinna, H. ; Aittomäki, K. ; Blomqvist, C. ; Hall, P. ; Czene, K. ; Irwanto, A. ; Liu, J. ; Rahman, N. ; Turnbull, C. ; Dunning, A.M. ; Pharoah, P. ; Waisfisz, Q. ; Meijers-Heijboer, H. ; Uitterlinden, A.G. ; Rivadeneira, F. ; Nicolae, D. ; Easton, D.F. ; Cox, N.J. ; Whittemore, A.S. / A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. In: Cancer Epidemiology Biomarkers and Prevention. 2014 ; Vol. 23, No. 4. pp. 658-669.

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title = "A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age",

author = "H. Ahsan and J. Halpern and M.G. Kibriya and B.L. Pierce and L. Tong and E. Gamazon and V. Mcguire and A. Felberg and J. Shi and F. Jasmine and S. Roy and R. Brutus and M. Argos and S. Melkonian and J. Chang-Claude and I. Andrulis and J.L. Hopper and E.M. John and K. Malone and G. Ursin and M.D. Gammon and D.C. Thomas and D. Seminara and G. Casey and J.A. Knight and M.C. Southey and G.G. Giles and R.M. Santella and E. Lee and D. Conti and D. Duggan and S. Gallinger and R. Haile and M. Jenkins and N.M. Lindor and P. Newcomb and K. Michailidou and C. Apicella and D.J. Park and J. Peto and O. Fletcher and I.D.S. Silva and M. Lathrop and D.J. Hunter and S.J. Chanock and A. Meindl and R.K. Schmutzler and B. M{\"u}ller-Myhsok and M. Lochmann and L. Beckmann and R. Hein and E. Makalic and D.F. Schmidt and Q.M. Bui and Jennifer Stone and D. Flesch-Janys and N. Dahmen and H. Nevanlinna and K. Aittom{\"a}ki and C. Blomqvist and P. Hall and K. Czene and A. Irwanto and J. Liu and N. Rahman and C. Turnbull and A.M. Dunning and P. Pharoah and Q. Waisfisz and H. Meijers-Heijboer and A.G. Uitterlinden and F. Rivadeneira and D. Nicolae and D.F. Easton and N.J. Cox and A.S. Whittemore",

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Ahsan, H, Halpern, J, Kibriya, MG, Pierce, BL, Tong, L, Gamazon, E, Mcguire, V, Felberg, A, Shi, J, Jasmine, F, Roy, S, Brutus, R, Argos, M, Melkonian, S, Chang-Claude, J, Andrulis, I, Hopper, JL, John, EM, Malone, K, Ursin, G, Gammon, MD, Thomas, DC, Seminara, D, Casey, G, Knight, JA, Southey, MC, Giles, GG, Santella, RM, Lee, E, Conti, D, Duggan, D, Gallinger, S, Haile, R, Jenkins, M, Lindor, NM, Newcomb, P, Michailidou, K, Apicella, C, Park, DJ, Peto, J, Fletcher, O, Silva, IDS, Lathrop, M, Hunter, DJ, Chanock, SJ, Meindl, A, Schmutzler, RK, Müller-Myhsok, B, Lochmann, M, Beckmann, L, Hein, R, Makalic, E, Schmidt, DF, Bui, QM, Stone, J, Flesch-Janys, D, Dahmen, N, Nevanlinna, H, Aittomäki, K, Blomqvist, C, Hall, P, Czene, K, Irwanto, A, Liu, J, Rahman, N, Turnbull, C, Dunning, AM, Pharoah, P, Waisfisz, Q, Meijers-Heijboer, H, Uitterlinden, AG, Rivadeneira, F, Nicolae, D, Easton, DF, Cox, NJ & Whittemore, AS 2014, 'A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age', Cancer Epidemiology Biomarkers and Prevention, vol. 23, no. 4, pp. 658-669. https://doi.org/10.1158/1055-9965.EPI-13-0340

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. / Ahsan, H.; Halpern, J.; Kibriya, M.G.; Pierce, B.L.; Tong, L.; Gamazon, E.; Mcguire, V.; Felberg, A.; Shi, J.; Jasmine, F.; Roy, S.; Brutus, R.; Argos, M.; Melkonian, S.; Chang-Claude, J.; Andrulis, I.; Hopper, J.L.; John, E.M.; Malone, K.; Ursin, G.; Gammon, M.D.; Thomas, D.C.; Seminara, D.; Casey, G.; Knight, J.A.; Southey, M.C.; Giles, G.G.; Santella, R.M.; Lee, E.; Conti, D.; Duggan, D.; Gallinger, S.; Haile, R.; Jenkins, M.; Lindor, N.M.; Newcomb, P.; Michailidou, K.; Apicella, C.; Park, D.J.; Peto, J.; Fletcher, O.; Silva, I.D.S.; Lathrop, M.; Hunter, D.J.; Chanock, S.J.; Meindl, A.; Schmutzler, R.K.; Müller-Myhsok, B.; Lochmann, M.; Beckmann, L.; Hein, R.; Makalic, E.; Schmidt, D.F.; Bui, Q.M.; Stone, Jennifer; Flesch-Janys, D.; Dahmen, N.; Nevanlinna, H.; Aittomäki, K.; Blomqvist, C.; Hall, P.; Czene, K.; Irwanto, A.; Liu, J.; Rahman, N.; Turnbull, C.; Dunning, A.M.; Pharoah, P.; Waisfisz, Q.; Meijers-Heijboer, H.; Uitterlinden, A.G.; Rivadeneira, F.; Nicolae, D.; Easton, D.F.; Cox, N.J.; Whittemore, A.S.

In: Cancer Epidemiology Biomarkers and Prevention, Vol. 23, No. 4, 2014, p. 658-669.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age

AU - Ahsan, H.

AU - Halpern, J.

AU - Kibriya, M.G.

AU - Pierce, B.L.

AU - Tong, L.

AU - Gamazon, E.

AU - Mcguire, V.

AU - Felberg, A.

AU - Shi, J.

AU - Jasmine, F.

AU - Roy, S.

AU - Brutus, R.

AU - Argos, M.

AU - Melkonian, S.

AU - Chang-Claude, J.

AU - Andrulis, I.

AU - Hopper, J.L.

AU - John, E.M.

AU - Malone, K.

AU - Ursin, G.

AU - Gammon, M.D.

AU - Thomas, D.C.

AU - Seminara, D.

AU - Casey, G.

AU - Knight, J.A.

AU - Southey, M.C.

AU - Giles, G.G.

AU - Santella, R.M.

AU - Lee, E.

AU - Conti, D.

AU - Duggan, D.

AU - Gallinger, S.

AU - Haile, R.

AU - Jenkins, M.

AU - Lindor, N.M.

AU - Newcomb, P.

AU - Michailidou, K.

AU - Apicella, C.

AU - Park, D.J.

AU - Peto, J.

AU - Fletcher, O.

AU - Silva, I.D.S.

AU - Lathrop, M.

AU - Hunter, D.J.

AU - Chanock, S.J.

AU - Meindl, A.

AU - Schmutzler, R.K.

AU - Müller-Myhsok, B.

AU - Lochmann, M.

AU - Beckmann, L.

AU - Hein, R.

AU - Makalic, E.

AU - Schmidt, D.F.

AU - Bui, Q.M.

AU - Stone, Jennifer

AU - Flesch-Janys, D.

AU - Dahmen, N.

AU - Nevanlinna, H.

AU - Aittomäki, K.

AU - Blomqvist, C.

AU - Hall, P.

AU - Czene, K.

AU - Irwanto, A.

AU - Liu, J.

AU - Rahman, N.

AU - Turnbull, C.

AU - Dunning, A.M.

AU - Pharoah, P.

AU - Waisfisz, Q.

AU - Meijers-Heijboer, H.

AU - Uitterlinden, A.G.

AU - Rivadeneira, F.

AU - Nicolae, D.

AU - Easton, D.F.

AU - Cox, N.J.

AU - Whittemore, A.S.

PY - 2014

Y1 - 2014

U2 - 10.1158/1055-9965.EPI-13-0340

DO - 10.1158/1055-9965.EPI-13-0340

M3 - Article

VL - 23

SP - 658

EP - 669

JO - Cancer Epidemiology, Biomarkers & Prevention

JF - Cancer Epidemiology, Biomarkers & Prevention

SN - 1055-9965

IS - 4

ER -