TY - JOUR
T1 - A fluid-structure interaction study using patient-specific ruptured and unruptured aneurysm
T2 - The effect of aneurysm morphology, hypertension and elasticity
AU - Lee, C. J.
AU - Zhang, Y.
AU - Takao, H.
AU - Murayama, Y.
AU - Qian, Y.
PY - 2013/9/27
Y1 - 2013/9/27
N2 - Fluid-structure interaction (FSI) simulations using five patient-specific aneurysm geometries are carried out to investigate the difference between ruptured and unruptured aneurysms. Two different blood pressure conditions (normal and hypertension, for all cases), and two different values of elastic modulus (1 and 2. MPa, for two cases) are tested. Ruptured aneurysms (RA) generally displayed larger displacement at the dome, lower area-average WSS and higher von Mises stress than unruptured aneurysms (URA) regardless of elasticity or blood pressure condition. RAs had a longitudinal expansion whereas URAs had a radial expansion, which was the key difference between the two types. The difference in expansion pattern may be one of the keys to explaining aneurysm rupture, and further analysis is required in the future to confirm this theory.
AB - Fluid-structure interaction (FSI) simulations using five patient-specific aneurysm geometries are carried out to investigate the difference between ruptured and unruptured aneurysms. Two different blood pressure conditions (normal and hypertension, for all cases), and two different values of elastic modulus (1 and 2. MPa, for two cases) are tested. Ruptured aneurysms (RA) generally displayed larger displacement at the dome, lower area-average WSS and higher von Mises stress than unruptured aneurysms (URA) regardless of elasticity or blood pressure condition. RAs had a longitudinal expansion whereas URAs had a radial expansion, which was the key difference between the two types. The difference in expansion pattern may be one of the keys to explaining aneurysm rupture, and further analysis is required in the future to confirm this theory.
KW - CFD
KW - Fluid-structure interaction (FSI)
KW - Intracranial aneurysm
UR - http://www.scopus.com/inward/record.url?scp=84883815785&partnerID=8YFLogxK
U2 - 10.1016/j.jbiomech.2013.07.016
DO - 10.1016/j.jbiomech.2013.07.016
M3 - Article
C2 - 23962529
AN - SCOPUS:84883815785
VL - 46
SP - 2402
EP - 2410
JO - Journal of Biomechanics
JF - Journal of Biomechanics
SN - 0021-9290
IS - 14
ER -