A fast liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QToF-MS) method for the identification of organic explosives and propellants

D. Detata, P. Collins, Allan Mckinley

Research output: Contribution to journalArticlepeer-review

62 Citations (Scopus)

Abstract

A fast, highly specific and sensitive method for the detection of an extensive list of organic explosives and propellants using an optimised Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (LC-QToF-MS) procedure has been developed. Analyte specific information including retention time, adduct accurate mass and fragmentation data was firstly collected using both positive and negative ion Atmospheric Pressure Chemical Ionisation (APCI) and entered into a Personal Compound Database/Library (PCDL). The custom PCDL can then be used to screen any sample for the presence of organic explosives and propellants, generating a match score for any identified compounds. To date over 50 organic explosives and propellants have been characterised and entered into the database representing those likely to be encountered in forensic and environmental samples and also a range of specialist explosives. © 2013 Elsevier Ireland Ltd.
Original languageEnglish
Pages (from-to)63-74
JournalForensic Science International
Volume233
Issue number1-3
DOIs
Publication statusPublished - 2013

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