A Domino Diels-Alder Approach toward the Tetracyclic Nicandrenone Framework

Emily G. MacKay, Marck Nörret, Leon S.M. Wong, Ignace Louis, Andrew L. Lawrence, Anthony C. Willis, Michael S. Sherburn

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The tetracarbocyclic framework of the nicandrenone natural products is formed in one step from a linear precursor via a domino intramolecular Diels-Alder/intramolecular furan Diels-Alder/aromatization sequence. The approach represents a new 0 → ABCD strategy for the preparation of aromatic steroids.

Original languageEnglish
Pages (from-to)5517-5519
Number of pages3
JournalOrganic Letters
Volume17
Issue number22
DOIs
Publication statusPublished - 20 Nov 2015
Externally publishedYes

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Aromatization
steroids
furans
Biological Products
Steroids
preparation
products
furan
nicandrenone

Cite this

MacKay, E. G., Nörret, M., Wong, L. S. M., Louis, I., Lawrence, A. L., Willis, A. C., & Sherburn, M. S. (2015). A Domino Diels-Alder Approach toward the Tetracyclic Nicandrenone Framework. Organic Letters, 17(22), 5517-5519. https://doi.org/10.1021/acs.orglett.5b02412
MacKay, Emily G. ; Nörret, Marck ; Wong, Leon S.M. ; Louis, Ignace ; Lawrence, Andrew L. ; Willis, Anthony C. ; Sherburn, Michael S. / A Domino Diels-Alder Approach toward the Tetracyclic Nicandrenone Framework. In: Organic Letters. 2015 ; Vol. 17, No. 22. pp. 5517-5519.
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MacKay, EG, Nörret, M, Wong, LSM, Louis, I, Lawrence, AL, Willis, AC & Sherburn, MS 2015, 'A Domino Diels-Alder Approach toward the Tetracyclic Nicandrenone Framework' Organic Letters, vol. 17, no. 22, pp. 5517-5519. https://doi.org/10.1021/acs.orglett.5b02412

A Domino Diels-Alder Approach toward the Tetracyclic Nicandrenone Framework. / MacKay, Emily G.; Nörret, Marck; Wong, Leon S.M.; Louis, Ignace; Lawrence, Andrew L.; Willis, Anthony C.; Sherburn, Michael S.

In: Organic Letters, Vol. 17, No. 22, 20.11.2015, p. 5517-5519.

Research output: Contribution to journalArticle

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