TY - JOUR
T1 - A chiral tetrahydro‐γ‐pyranonecarboxylate ester for asymmetric Nazarov cyclization
AU - Bond, Charles S
AU - Leonard, G.A.
AU - Regan, A.C.
AU - Hunter, W.N.
AU - Andrews, J.F.P.
PY - 1994/1
Y1 - 1994/1
N2 - (1S,2-exo)-1-[(N,N-Dicyclohexylamino)sulfonylme-thyl]-7,7-dimethylbicyclo[2.2.1]heptan-2-yl [2R(2alpha,-3beta,5beta,6alpha)]-tetrahydro-2,5,6-trimethyl-4-oxo-2H-py-ran-3-carboxylate, C31H51NO6S, has an asymmetric unit containing two unique but similarly conformed molecules (A and B). In molecule A the cyclohexyl rings are free to crystallize in either of the approximately coplanar conformations. whereas in molecule B only one conformation is allowed. The N atoms in each molecule have approximately planar geometries, as expected from previous related structures. The tetrahydropyranone ring adopts the chair conformation with all substituents equatorial.
AB - (1S,2-exo)-1-[(N,N-Dicyclohexylamino)sulfonylme-thyl]-7,7-dimethylbicyclo[2.2.1]heptan-2-yl [2R(2alpha,-3beta,5beta,6alpha)]-tetrahydro-2,5,6-trimethyl-4-oxo-2H-py-ran-3-carboxylate, C31H51NO6S, has an asymmetric unit containing two unique but similarly conformed molecules (A and B). In molecule A the cyclohexyl rings are free to crystallize in either of the approximately coplanar conformations. whereas in molecule B only one conformation is allowed. The N atoms in each molecule have approximately planar geometries, as expected from previous related structures. The tetrahydropyranone ring adopts the chair conformation with all substituents equatorial.
U2 - 10.1107/S0108270193006468
DO - 10.1107/S0108270193006468
M3 - Article
SN - 1600-5759
VL - 50
SP - 133
EP - 136
JO - Acta Crystallographica. Section C: Crystal Structure Communications
JF - Acta Crystallographica. Section C: Crystal Structure Communications
ER -