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  • Jiake Xu
2018

Achyranthes bidentata polysaccharide suppresses osteoclastogenesis and bone resorption via inhibiting RANKL signaling

Song, D., Cao, Z., Huang, S., Tickner, J., Li, N., Qiu, H., Chen, X., Wang, C., Chen, K., Sun, Y., Dong, S. & Xu, J., 1 Jun 2018, In : Journal of Cellular Biochemistry. 119, 6, p. 4826-4835 10 p.

Research output: Contribution to journalArticle

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7 Citations (Scopus)
314 Downloads (Pure)

Artesunate inhibits RANKL-induced osteoclastogenesis and bone resorption in vitro and prevents LPS-induced bone loss in vivo

Wei, C. M., Liu, Q., Song, F. M., Lin, X. X., Su, Y. J., Xu, J., Huang, L., Zong, S. H. & Zhao, J. M., 1 Jan 2018, In : Journal of Cellular Physiology. 233, 1, p. 476-485 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Carnosic acid inhibits inflammation response and joint destruction on osteoclasts, fibroblast-like synoviocytes, and collagen-induced arthritis rats

Liu, M., Zhou, X., Zhou, L., Liu, Z., Yuan, J., Cheng, J., Zhao, J., Wu, L., Li, H., Qiu, H. & Xu, J., 1 Aug 2018, In : Journal of Cellular Physiology. 233, 8, p. 6291-6303 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption via inhibiting RANKL signaling and reactive oxygen species production

Song, D., Cao, Z., Liu, Z., Tickner, J., Qiu, H., Wang, C., Chen, K., Wang, Z., Dong, S. & Xu, J., 1 Dec 2018, In : Journal of Cellular Physiology. 233, 12, p. 9674-9684 11 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
124 Downloads (Pure)
17 Citations (Scopus)

Coupling factors and exosomal packaging microRNAs involved in the regulation of bone remodelling

Zhu, S., Yao, F., Qiu, H., Zhang, G., Xu, H. & Xu, J., Feb 2018, In : Biological Reviews. 93, 1, p. 469-480 12 p.

Research output: Contribution to journalArticle

Open Access
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21 Citations (Scopus)
437 Downloads (Pure)

Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways

Cheng, J., Zhou, L., Liu, Q., Tickner, J., Tan, Z., Li, X., Liu, M., Lin, X., Wang, T., Pavlos, N. J., Zhao, J. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2502-2512 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis

Hong, G., Kuek, V., Shi, J., Zhou, L., Han, X., He, W., Tickner, J., Qiu, H., Wei, Q. & Xu, J., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8526-8537 12 p.

Research output: Contribution to journalReview article

Open Access
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6 Citations (Scopus)
204 Downloads (Pure)

Expression quantitative trait locus study of bone mineral density GWAS variants in human osteoclasts

Mullin, B. H., Zhu, K., Xu, J., Brown, S. J., Mullin, S., Tickner, J., Pavlos, N. J., Dudbridge, F., Walsh, J. P. & Wilson, S. G., Jun 2018, In : Journal of Bone & Mineral Research. 33, 6, p. 1044-1051

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
417 Downloads (Pure)

GdX/UBL4A null mice exhibit mild kyphosis and scoliosis accompanied by dysregulation of osteoblastogenesis and chondrogenesis

Liang, J., Li, J., Fu, Y., Ren, F., Xu, J., Zhou, M., Li, P., Feng, H. & Wang, Y., 1 Apr 2018, In : Cell Biochemistry and Function. 36, 3, p. 129-136 8 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
225 Downloads (Pure)

Green synthesis of lignin nanoparticle in aqueous hydrotropic solution toward broadening the window for its processing and application

Chen, L., Zhou, X., Shi, Y., Gao, B., Wu, J., Kirk, T. B., Xu, J. & Xue, W., 15 Aug 2018, In : Chemical Engineering Journal. 346, p. 217-225 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Inhibitory effects of tubeimoside I on synoviocytes and collagen-induced arthritis in rats

Liu, Z., Zhou, L., Ma, X., Sun, S., Qiu, H., Li, H., Xu, J. & Liu, M., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8740-8753 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Light-Triggered Biomimetic Nanoerythrocyte for Tumor-Targeted Lung Metastatic Combination Therapy of Malignant Melanoma

Liu, W., Ruan, M., Wang, Y., Song, R., Ji, X., Xu, J., Dai, J. & Xue, W., 20 Sep 2018, In : Small. 14, 38, 1801754.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Lumichrome inhibits osteoclastogenesis and bone resorption through suppressing RANKL-induced NFAT activation and calcium signaling

Liu, C., Cao, Z., Zhang, W., Tickner, J., Qiu, H., Wang, C., Chen, K., Wang, Z., Tan, R., Dong, S. & Xu, J., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8971-8983 13 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
129 Downloads (Pure)

Luteoloside prevents lipopolysaccharide-induced osteolysis and suppresses RANKL-induced osteoclastogenesis through attenuating RANKL signaling cascades

Song, F., Wei, C., Zhou, L., Qin, A., Yang, M., Tickner, J., Huang, Y., Zhao, J. & Xu, J., 1 Feb 2018, In : Journal of Cellular Physiology. 233, 2, p. 1723-1735 13 p.

Research output: Contribution to journalArticle

Open Access
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14 Citations (Scopus)
227 Downloads (Pure)

Macrophages release plasma membrane-derived particles rich in accessible cholesterol

He, C., Hu, X., Weston, T. A., Jung, R. S., Sandhu, J., Huang, S., Heizer, P., Kim, J., Ellison, R., Xu, J., Kilburn, M., Bensinger, S. J., Riezman, H., Tontonoz, P., Fong, L. G., Jiang, H. & Young, S. G., 4 Sep 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 36, p. E8499-E8508

Research output: Contribution to journalArticle

6 Citations (Scopus)

MicroRNAs as Potential Targets for Treatment of Osteoclast-Related Diseases

Li, H., Zhai, Z., Qu, X., Xu, J., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 422-431 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Monocrotaline Suppresses RANKL-Induced Osteoclastogenesis in Vitro and Prevents LPS-Induced Bone Loss in Vivo

Wei, C. M., Su, Y. J., Qin, X., Ding, J. X., Liu, Q., Song, F. M., Zong, S. H., Xu, J., Zhou, B. & Zhao, J. M., 1 Aug 2018, In : Cellular Physiology and Biochemistry. 48, 2, p. 644-656 13 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Osteoblast derived-neurotrophin‑3 induces cartilage removal proteases and osteoclast-mediated function at injured growth plate in rats

Su, Y. W., Chim, S. M., Zhou, L., Hassanshahi, M., Chung, R., Fan, C., Song, Y., Foster, B. K., Prestidge, C. A., Peymanfar, Y., Tang, Q., Butler, L. M., Gronthos, S., Chen, D., Xie, Y., Chen, L., Zhou, X. F., Xu, J. & Xian, C. J., 1 Nov 2018, In : Bone. 116, p. 232-247 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Poria cocos polysaccharide attenuates RANKL-induced osteoclastogenesis by suppressing NFATc1 activity and phosphorylation of ERK and STAT3

Song, D., Cao, Z., Tickner, J., Qiu, H., Wang, C., Chen, K., Wang, Z., Guo, C., Dong, S. & Xu, J., 1 Jun 2018, In : Archives of Biochemistry and Biophysics. 647, p. 76-83 8 p.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
186 Downloads (Pure)

Redox-responsive chemosensitive polyspermine delivers ursolic acid targeting to human breast tumor cells: The depletion of intracellular GSH contents arouses chemosensitizing effects

Ji, X., Tang, Q., Pang, P., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 1 Oct 2018, In : Colloids and Surfaces B: Biointerfaces. 170, p. 293-302 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Reduction-Responsive Codelivery System Based on a Metal-Organic Framework for Eliciting Potent Cellular Immune Response

Yang, Y., Chen, Q., Wu, J-P., Kirk, T. B., Xu, J., Liu, Z. & Xue, W., 18 Apr 2018, In : ACS APPLIED MATERIALS & INTERFACES. 10, 15, p. 12463-12473 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Rheumatoid arthritis: Pathological mechanisms and modern pharmacologic therapies

Guo, Q., Wang, Y., Xu, D., Nossent, J., Pavlos, N. J. & Xu, J., 1 Dec 2018, In : Bone Research. 6, 1, 16.

Research output: Contribution to journalReview article

Open Access
98 Citations (Scopus)

Roles of neurotrophins in skeletal tissue formation and healing

Su, Y. W., Zhou, X. F., Foster, B. K., Grills, B. L., Xu, J. & Xian, C. J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2133-2145 13 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

Synthesis of Janus Au nanorods/polydivinylbenzene hybrid nanoparticles for chemo-photothermal therapy

Wang, Y., Ji, X., Pang, P., Shi, Y., Dai, J., Xu, J., Wu, J., Kirk, T. B. & Xue, W., 28 Apr 2018, In : Journal of Materials Chemistry B. 6, 16, p. 2481-2488 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The emerging role of Hippo signaling pathway in regulating osteoclast formation

Yang, W., Han, W., Qin, A., Wang, Z., Xu, J. & Qian, Y., 1 Jun 2018, In : Journal of Cellular Physiology. 233, 6, p. 4606-4617 12 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

The emerging role of NPNT in tissue injury repair and bone homeostasis

Sun, Y., Kuek, V., Qiu, H., Tickner, J., Chen, L., Wang, H., He, W. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 1887-1894 8 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

TNF-α inhibits SATB2 expression and osteoblast differentiation through NF-κB and MAPK pathways

Zuo, C., Zhao, X., Shi, Y., Wu, W., Zhang, N., Xu, J., Wang, C., Hu, G. & Zhang, X., 1 Jan 2018, In : Oncotarget. 9, 4, p. 4833-4850 18 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42

Xu, S., Zhang, Y., Wang, J., Li, K., Tan, K., Liang, K., Shen, J., Cai, D., Jin, D., Li, M., Xiao, G., Xu, J., Jiang, Y. & Bai, X., Sep 2018, In : Cell Death and Differentiation. 25, 9, p. 1549–1566

Research output: Contribution to journalArticle

2 Citations (Scopus)

Zoledronic Acid: Pleiotropic Anti-tumor Mechanism and Therapeutic Outlook for Osteosarcoma

Ouyang, Z., Li, H., Zhai, Z., Xu, J., Dass, C. R., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 409-421 13 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
2017

A polyamidoamne dendrimer functionalized graphene oxide for DOX and MMP-9 shRNA plasmid co-delivery

Gu, Y., Guo, Y., Wang, C., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Jan 2017, In : Materials Science and Engineering C. 70, p. 572-585 14 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca2+–NFATc1 signaling pathway and prevents ovariectomy-induced bone loss

Zeng, X., Zhang, Y., Wang, S., Wang, K., Tao, L., Zou, M., Chen, N., Xu, J., Liu, S. & Li, X., 15 Jan 2017, In : Biochemical Pharmacology. 124, p. 57-68 12 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Bajijiasu abrogates osteoclast differentiation via the suppression of RANKL signaling pathways through NF-κB and NFAT

Hong, G., Zhou, L., Shi, X., He, W., Wang, H., Wei, Q., Chen, P., Qi, L., Tickner, J., Lin, L. & Xu, J., 19 Jan 2017, In : International Journal of Molecular Sciences. 18, 1, 12 p., 203.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Biocompatibility and cellular uptake mechanisms of poly(N -isopropylacrylamide) in different cells

Guo, Z., Li, S., Wang, C., Xu, J., Kirk, B., Wu, J., Liu, Z. & Xue, W., 1 Jan 2017, In : Journal of Bioactive and Compatible Polymers. 32, 1, p. 17-31 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Biocompatible hyperbranched polyglycerol modified β-cyclodextrin derivatives for docetaxel delivery

Xu, Z., Zhang, Y., Hu, Q., Tang, Q., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Feb 2017, In : Materials Science and Engineering C. 71, p. 965-972 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

CHIP/Stub1 regulates the Warburg effect by promoting degradation of PKM2 in ovarian carcinoma

Shang, Y., He, J., Wang, Y., Feng, Q., Zhang, Y., Guo, J., Li, J., Li, S., Wang, Y., Yan, G., Ren, F., Shi, Y., Xu, J., Zeps, N., Zhai, Y., He, D. & Chang, Z., 20 Jul 2017, In : Oncogene. 36, 29, p. 4191-4200 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Differential protein expression between normal and degenerated human nucleus pulposus cells by proteomic and bioinformatics analyses

Ye, D. P., Liang, W. G., Dai, L., Yao, Y., Chen, H., Zhou, Y. & Xu, J., 2017, In : International Journal of Clinical and Experimental Medicine. 10, 12, p. 16172-16180 9 p.

Research output: Contribution to journalArticle

Open Access
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56 Downloads (Pure)

Evaluation of N-phosphonium chitosan as a novel vaccine carrier for intramuscular immunization

Cai, J., Zhang, W., Xu, J., Xue, W. & Liu, Z., 1 Nov 2017, In : Journal of Biomaterials Applications. 32, 5, p. 677-685 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Hemostasis mechanism and applications of N-alkylated chitosan sponge

Huang, Y., Feng, L., Zhang, Y., He, L., Wang, C., Xu, J., Wu, J., Kirk, T. B., Guo, R. & Xue, W., 1 Sep 2017, In : Polymers for Advanced Technologies. 28, 9, p. 1107-1114 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

High-resolution study of the 3D collagen fibrillary matrix of Achilles tendons without tissue labelling and dehydrating

Wu, J. P., Swift, B. J., Becker, T., Squelch, A., Wang, A., Zheng, Y. C., Zhao, X., Xu, J., Xue, W., Zheng, M., Lloyd, D. & Kirk, T. B., Jun 2017, In : Journal of Microscopy. 266, 3, p. 237-287

Research output: Contribution to journalArticle

3 Citations (Scopus)

Injectable supramolecular hydrogel formed from α-cyclodextrin and PEGylated arginine-functionalized poly(L-lysine) dendron for sustained MMP-9 shRNA plasmid delivery

Lin, Q., Yang, Y., Hu, Q., Guo, Z., Liu, T., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Feb 2017, In : Acta Biomaterialia. 49, p. 456-471 16 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Massage alleviates delayed onset muscle soreness after strenuous exercise: A systematic review and meta-analysis

Guo, J., Li, L., Gong, Y., Zhu, R., Xu, J., Zou, J. & Chen, X., 27 Sep 2017, In : Frontiers in Physiology. 8, 747.

Research output: Contribution to journalReview article

Open Access
8 Citations (Scopus)

Mechanical Stress Regulates Bone Metabolism Through MicroRNAs

Yuan, Y., Zhang, L., Tong, X., Zhang, M., Zhao, Y., Guo, J., Lei, L., Chen, X., Tickner, J., Xu, J. & Zou, J., 1 Jun 2017, In : Journal of Cellular Physiology. 232, 6, p. 1239-1245 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Melphalan modifies the bone microenvironment by enhancing osteoclast formation

Chai, R. C., McDonald, M. M., Terry, R. L., Kovacic, N., Down, J. M., Pettitt, J. A., Mohanty, S. T., Shah, S., Haffari, G., Xu, J., Gillespie, M. T., Rogers, M. J., Price, J. T., Croucher, P. I. & Quinn, J. M. W., 15 Sep 2017, In : Oncotarget. 8, 40, p. 68047-68058 12 p.

Research output: Contribution to journalArticle

Open Access

Molecular structure and differential function of choline kinases CHKα and CHKβ in musculoskeletal system and cancer

Chen, X., Qiu, H., Wang, C., Yuan, Y., Tickner, J., Xu, J. & Zou, J., Feb 2017, In : Cytokine and Growth Factor Reviews. 33, p. 65-72 8 p.

Research output: Contribution to journalReview article

Open Access
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1 Citation (Scopus)
269 Downloads (Pure)

Natural Compounds for the Treatment of Psoriatic Arthritis: A Proposal Based on Multi-Targeted Osteoclastic Regulation and on a Preclinical Study

Deng, S., Cheng, J., Zhao, J., Yao, F. & Xu, J., 11 Jul 2017, In : JMIR Research Protocols. 6, 7, e132.

Research output: Contribution to journalArticle

Open Access

Neohesperidin suppresses osteoclast differentiation, bone resorption and ovariectomised-induced osteoporosis in mice

Tan, Z., Cheng, J., Liu, Q., Zhou, L., Kenny, J., Wang, T., Lin, X., Yuan, J., Quinn, J. M. W., Tickner, J., Hong, G., Qin, A., Zhao, J. & Xu, J., 5 Jan 2017, In : Molecular and Cellular Endocrinology. 439, p. 369-378 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The Emerging Role of MORC Family Proteins in Cancer Development and Bone Homeostasis

Hong, G., Qiu, H., Wang, C., Jadhav, G., Wang, H., Tickner, J., He, W. & Xu, J., 1 May 2017, In : Journal of Cellular Physiology. 232, 5, p. 928-934 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Therapeutic potential and outlook of alternative medicine for osteoporosis

Wang, T., Liu, Q., Tjhioe, W., Zhao, J., Lu, A., Zhang, G., Tan, R. X., Zhou, M., Xu, J. & Feng, H. T., 1 Jul 2017, In : Current Drug Targets. 18, 9, p. 1051-1068 18 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)