Find Research Outputs

Search concepts
Selected filters

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Jiake Xu
2019

A005, a novel inhibitor of phosphatidylinositol 3-kinase/mammalian target of rapamycin, prevents osteosarcoma-induced osteolysis

Lian, Z., Han, J., Huang, L., Wei, C., Fan, Y., Xu, J., Zhou, M., Feng, H., Liu, Q., Chen, L., Li, Z., Cheng, H., Yuan, G., Lin, X., Song, F., Su, Y., Wang, C., Huang, G., Qin, A., Song, Y. & 1 others, Yao, G., 1 Jan 2019, In : Carcinogenesis. 40, 2, p. E1-E13

Research output: Contribution to journalArticle

2 Citations (Scopus)

Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human

Yuan, J., Tickner, J., Mullin, B. H., Zhao, J., Zeng, Z., Morahan, G. & Xu, J., 2 Apr 2019, In : Frontiers in Genetics. 10, 13 p., 288.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Analysis of circulating microRNAs aberrantly expressed in alcohol-induced osteonecrosis of femoral head

Hong, G., Han, X., He, W., Xu, J., Sun, P., Shen, Y., Wei, Q. & Chen, Z., 1 Dec 2019, In : Scientific Reports. 9, 1, 18926.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Asiaticoside, a component of Centella asiatica attenuates RANKL-induced osteoclastogenesis via NFATc1 and NF-kappa B signaling pathways

He, L., Hong, G., Zhou, L., Zhang, J., Fang, J., He, W., Tickner, J., Han, X., Zhao, L. & Xu, J., Apr 2019, In : Journal of Cellular Physiology. 234, 4, p. 4267-4276 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Asperpyrone A attenuates RANKL-induced osteoclast formation through inhibiting NFATc1, Ca2+ signalling and oxidative stress

Chen, X., Wang, C., Qiu, H., Yuan, Y., Chen, K., Cao, Z., Xiang Tan, R., Tickner, J., Xu, J. & Zou, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8269-8279 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis

Jin, H., Wang, Q., Chen, K., Xu, K., Pan, H., Chu, F., Ye, Z., Wang, Z., Tickner, J., Qiu, H., Wang, C., Kenny, J., Xu, H., Wang, T. & Xu, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8355-8368 14 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Cajaninstilbene acid inhibits osteoporosis through suppressing osteoclast formation and RANKL-induced signaling pathways

Sun, Y., Liu, Y., He, W., Wang, C., Tickner, J., Kuek, V., Zhou, C., Wang, H., Zou, X., Hong, Z., Yang, F., Shao, M., Chen, L. & Xu, J., 1 Jul 2019, In : Journal of Cellular Physiology. 234, 7, p. 11792-11804 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cepharanthine suppresses osteoclast formation by modulating the nuclear factor-κB and nuclear factor of activated T-cell signaling pathways

Lin, X., Song, F., Zhou, L., Wang, Z., Wei, C., Xu, J., Zhao, J. & Liu, Q., 1 Feb 2019, In : Journal of Cellular Biochemistry. 120, 2, p. 1990-1996 7 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
42 Downloads (Pure)

Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease

Zhu, S., Qiu, H., Bennett, S., Kuek, V., Rosen, V., Xu, H. & Xu, J., Nov 2019, In : Cellular and Molecular Life Sciences. 76, 22, p. 4493-4502

Research output: Contribution to journalReview article

Open Access

Connecting Versatile lncRNAs with Heterogeneous Nuclear Ribonucleoprotein K and Pathogenic Disorders

Zhu, S., Wang, Z. & Xu, J., 1 Sep 2019, In : Trends in Biochemical Sciences. 44, 9, p. 733-736 4 p.

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Cumambrin A prevents OVX-induced osteoporosis via the inhibition of osteoclastogenesis, bone resorption, and RANKL signaling pathways

Zhou, L., Liu, Q., Hong, G., Song, F., Zhao, J., Yuan, J., Xu, J., Tan, R. X., Tickner, J., Gu, Q. & Xu, J., 1 Jun 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 6, p. 6726-6735 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Cytochalasin Z11 inhibits RANKL-induced osteoclastogenesis: Via suppressing NFATc1 activation

Wang, L., Chen, K., He, J., Kenny, J., Yuan, Y., Chen, J., Liu, Q., Tan, R., Zhao, J. & Xu, J., 25 Nov 2019, In : RSC Advances. 9, 66, p. 38438-38446 9 p.

Research output: Contribution to journalArticle

Open Access

Daphnetin attenuates LPS-induced osteolysis and RANKL mediated osteoclastogenesis through suppression of ERK and NFATc1 pathways

Wu, Z., Wu, H., Li, C., Fu, F., Ding, J., Shao, S., Li, K., Yu, X., Su, Y., Liang, J., Lin, X., Yuan, G., Zhou, J., Song, F., Zhao, J., Xu, J., Liu, Q. & Xu, F., 1 Oct 2019, In : Journal of Cellular Physiology. 234, 10, p. 17812-17823 12 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Dehydrocostus lactone (DHC) suppresses estrogen deficiency-induced osteoporosis

Li, Z., Yuan, G., Lin, X., Liu, Q., Xu, J., Lian, Z., Song, F., Zheng, J., Xie, D., Chen, L., Wang, X., Feng, H., Zhou, M. & Yao, G., 1 May 2019, In : Biochemical Pharmacology. 163, p. 279-289 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Diosmetin inhibits osteoclast formation and differentiation and prevents LPS-induced osteolysis in mice

Shao, S., Fu, F., Wang, Z., Song, F., Li, C., Wu, Z. X., Ding, J., Li, K., Xiao, Y., Su, Y., Lin, X., Yuan, G., Zhao, J., Liu, Q. & Xu, J., 1 Aug 2019, In : Journal of Cellular Physiology. 234, 8, p. 12701-12713 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Discovery of new inhibitors against both NF-κB and osteoclastogenesis from in-house library with α, β-unsaturated-enone fragment

Zhao, C., Huang, D., Li, R., Xu, J., Gu, Q. & Xu, J., 1 Jun 2019, In : Bioorganic Chemistry. 87, p. 638-646 9 p.

Research output: Contribution to journalArticle

Double network shape memory hydrogels activated by near-infrared with high mechanical toughness, nontoxicity, and 3D printability

Dai, W., Guo, H., Gao, B., Ruan, M., Xu, L., Wu, J., Kirk, T. B., Xu, J., Ma, D. & Xue, W., 15 Jan 2019, In : Chemical Engineering Journal. 356, p. 934-949 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Emerging Trend in the Pharmacotherapy of Osteoarthritis

Zhang, W., Robertson, W. B., Zhao, J., Chen, W. & Xu, J., 2 Jul 2019, In : Frontiers in Endocrinology. 10, 9 p., 431.

Research output: Contribution to journalReview article

Open Access
8 Citations (Scopus)

Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice

Jin, H., Yao, L., Chen, K., Liu, Y., Wang, Q., Wang, Z., Liu, Q., Cao, Z., Kenny, J., Tickner, J., Wang, X. & Xu, J., Jan 2019, In : Journal of Cellular and Molecular Medicine. 23, 1, p. 522-534 13 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
Open Access
3 Citations (Scopus)

Helvolic acid attenuates osteoclast formation and function via suppressing RANKL-induced NFATc1 activation

Chen, K., Yuan, Y., Wang, Z., Song, D., Zhao, J., Cao, Z., Chen, J., Guo, Q., Chen, L., Tickner, J. & Xu, J., May 2019, In : Journal of Cellular Physiology. 234, 5, p. 6477-6488 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
15 Downloads (Pure)

Loureirin B suppresses RANKL-induced osteoclastogenesis and ovariectomized osteoporosis via attenuating NFATc1 and ROS activities

Liu, Y., Wang, C., Wang, G., Sun, Y., Deng, Z., Chen, L., Chen, K., Tickner, J., Kenny, J., Song, D., Zhang, Q., Wang, H., Chen, Z., Zhou, C., He, W. & Xu, J., 2019, In : Theranostics. 9, 16, p. 4648-4662 15 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Madecassoside inhibits estrogen deficiency-induced osteoporosis by suppressing RANKL-induced osteoclastogenesis

Wang, Q., Yao, L., Xu, K., Jin, H., Chen, K., Wang, Z., Liu, Q., Cao, Z., Kenny, J., Liu, Y., Tickner, J., Xu, H. & Xu, J., Jan 2019, In : Journal of Cellular and Molecular Medicine. 23, 1, p. 380-394 15 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

MiR-214 Attenuates the Osteogenic Effects of Mechanical Loading on Osteoblasts

Yuan, Y., Guo, J., Zhang, L., Tong, X., Zhang, S., Zhou, X., Zhang, M., Chen, X., Lei, L., Li, H., Liu, T. C. Y., Xu, J. & Zou, J., Dec 2019, In : International Journal of Sports Medicine. 40, 14, p. 931-940 10 p.

Research output: Contribution to journalArticle

MiR-214 is an important regulator of the musculoskeletal metabolism and disease

Sun, Y., Kuek, V., Liu, Y., Tickner, J., Yuan, Y., Chen, L., Zeng, Z., Shao, M., He, W. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 231-245 15 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Modulating calcium-mediated NFATc1 and mitogen-activated protein kinase deactivation underlies the inhibitory effects of kavain on osteoclastogenesis and bone resorption

Guo, Q., Cao, Z., Wu, B., Chen, F., Tickner, J., Wang, Z., Qiu, H., Wang, C., Chen, K., Tan, R., Gao, Q. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 789-801 13 p.

Research output: Contribution to journalArticle

File
5 Citations (Scopus)
191 Downloads (Pure)

Molecular structure and the role of high-temperature requirement protein 1 in skeletal disorders and cancers

Li, Y., Yuan, J., Rothzerg, E., Wu, X., Xu, H., Zhu, S. & Xu, J., 22 Dec 2019, In : Cell Proliferation. e12746.

Research output: Contribution to journalReview article

Open Access

Osthole inhibits osteoclasts formation and bone resorption by regulating NF-κB signaling and NFATc1 activations stimulated by RANKL

Ma, Y., Wang, L., Zheng, S., Xu, J., Pan, Y., Tu, P., Sun, J. & Guo, Y., 1 Sep 2019, In : Journal of Cellular Biochemistry. 120, 9, p. 16052-16061 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Pathological mechanisms and therapeutic outlooks for arthrofibrosis

Usher, K. M., Zhu, S., Mavropalias, G., Carrino, J. A., Zhao, J. & Xu, J., 1 Dec 2019, In : Bone Research. 7, 1, 9.

Research output: Contribution to journalReview article

Open Access
6 Citations (Scopus)

Pectolinarigenin prevents bone loss in ovariectomized mice and inhibits RANKL-induced osteoclastogenesis via blocking activation of MAPK and NFATc1 signaling

Xiao, Y., Li, K., Wang, Z., Fu, F., Shao, S., Song, F., Zhao, J., Chen, W., Liu, Q. & Xu, J., 1 Aug 2019, In : Journal of Cellular Physiology. 234, 8, p. 13959-13968 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

PIP5k1 beta controls bone homeostasis through modulating both osteoclast and osteoblast differentiation

Zhao, X., Cui, P., Wang, C., Zhao, J., Zhang, X. & Xu, J., Dec 2019, In : Journal of Bone and Mineral Research. 34, p. 328-328 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Protein Cytl1: its role in chondrogenesis, cartilage homeostasis, and disease

Zhu, S., Kuek, V., Bennett, S., Xu, H., Rosen, V. & Xu, J., 14 May 2019, In : Cellular and Molecular Life Sciences. 76, 18, p. 3515-3523

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Pseurotin A inhibits osteoclastogenesis and prevents ovariectomized-induced bone loss by suppressing reactive oxygen species

Chen, K., Qiu, P., Yuan, Y., Zheng, L., He, J., Wang, C., Guo, Q., Kenny, J., Liu, Q., Zhao, J., Chen, J., Tickner, J., Fan, S., Lin, X. & Xu, J., 28 Feb 2019, In : Theranostics. 9, 6, p. 1634-1650

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
390 Downloads (Pure)

Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways

Liao, S., Song, F., Feng, W., Ding, X., Yao, J., Song, H., Liu, Y., Ma, S., Wang, Z., Lin, X., Xu, J., Zhao, J. & Liu, Q., 1 Oct 2019, In : Journal of Cellular Physiology. 234, 10, p. 17600-17611 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Salidroside promotes rat spinal cord injury recovery by inhibiting inflammatory cytokine expression and NF-κB and MAPK signaling pathways

Su, Y., Zong, S., Wei, C., Song, F., Feng, H., Qin, A., Lian, Z., Fu, F., Shao, S., Fang, F., Wu, T., Xu, J., Liu, Q. & Zhao, J., 1 Aug 2019, In : Journal of Cellular Physiology. 234, 8, p. 14259-14269 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Sclareol prevents ovariectomy-induced bone loss: In vivo and inhibits osteoclastogenesis in vitro via suppressing NF-κB and MAPK/ERK signaling pathways

Jin, H., Shao, Z., Wang, Q., Miao, J., Bai, X., Liu, Q., Qiu, H., Wang, C., Zhang, Z., Jennifer, T., Wang, X. & Xu, J., 1 Oct 2019, In : Food and Function. 10, 10, p. 6556-6567 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Scutellarein inhibits RANKL-induced osteoclast formation in vitro and prevents LPS-induced bone loss in vivo

Fu, F., Shao, S., Wang, Z., Song, F., Lin, X., Ding, J., Li, C., Wu, Z., Li, K., Xiao, Y., Su, Y., Zhao, J., Liu, Q. & Xu, J., 1 Jul 2019, In : Journal of Cellular Physiology. 234, 7, p. 11951-11959 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
122 Downloads (Pure)

The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis

Tong, X., Chen, X., Zhang, S., Huang, M., Shen, X., Xu, J. & Zou, J., 2019, In : BioMed Research International. 2019, 8 p., 8171897.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

The emerging roles of hnRNPK

Wang, Z., Qiu, H., He, J., Liu, L., Xue, W., Fox, A., Tickner, J. & Xu, J., 19 Sep 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Therapeutic anabolic and anticatabolic benefits of natural Chinese medicines for the treatment of osteoporosis

He, J., Li, X., Wang, Z., Bennett, S., Chen, K., Xiao, Z., Zhan, J., Chen, S., Hou, Y., Chen, J., Wang, S., Xu, J. & Lin, D., 25 Nov 2019, In : Frontiers in Pharmacology. 10, 1344.

Research output: Contribution to journalArticle

Open Access

Tiliroside is a new potential therapeutic drug for osteoporosis in mice

Li, K., Xiao, Y., Wang, Z., Fu, F., Shao, S., Song, F., Zhao, J., Lin, X., Liu, Q. & Xu, J., 1 Sep 2019, In : Journal of Cellular Physiology. 234, 9, p. 16263-16274 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Vaccarin prevents titanium particle-induced osteolysis and inhibits RANKL-induced osteoclastogenesis by blocking NF-κB and MAPK signaling pathways

Liu, Y., Song, F. M., Ma, S. T., Moro, A., Feng, W. Y., Liao, S. J., Lin, X. X., Zhao, J. M., Wang, Z. Y., Xu, J., Zhan, X. L. & Liu, Q., 1 Aug 2019, In : Journal of Cellular Physiology. 234, 8, p. 13832-13842 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2018

Achyranthes bidentata polysaccharide suppresses osteoclastogenesis and bone resorption via inhibiting RANKL signaling

Song, D., Cao, Z., Huang, S., Tickner, J., Li, N., Qiu, H., Chen, X., Wang, C., Chen, K., Sun, Y., Dong, S. & Xu, J., 1 Jun 2018, In : Journal of Cellular Biochemistry. 119, 6, p. 4826-4835 10 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
321 Downloads (Pure)

Artesunate inhibits RANKL-induced osteoclastogenesis and bone resorption in vitro and prevents LPS-induced bone loss in vivo

Wei, C. M., Liu, Q., Song, F. M., Lin, X. X., Su, Y. J., Xu, J., Huang, L., Zong, S. H. & Zhao, J. M., 1 Jan 2018, In : Journal of Cellular Physiology. 233, 1, p. 476-485 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Carnosic acid inhibits inflammation response and joint destruction on osteoclasts, fibroblast-like synoviocytes, and collagen-induced arthritis rats

Liu, M., Zhou, X., Zhou, L., Liu, Z., Yuan, J., Cheng, J., Zhao, J., Wu, L., Li, H., Qiu, H. & Xu, J., 1 Aug 2018, In : Journal of Cellular Physiology. 233, 8, p. 6291-6303 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption via inhibiting RANKL signaling and reactive oxygen species production

Song, D., Cao, Z., Liu, Z., Tickner, J., Qiu, H., Wang, C., Chen, K., Wang, Z., Dong, S. & Xu, J., 1 Dec 2018, In : Journal of Cellular Physiology. 233, 12, p. 9674-9684 11 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
128 Downloads (Pure)
17 Citations (Scopus)

Coupling factors and exosomal packaging microRNAs involved in the regulation of bone remodelling

Zhu, S., Yao, F., Qiu, H., Zhang, G., Xu, H. & Xu, J., Feb 2018, In : Biological Reviews. 93, 1, p. 469-480 12 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
437 Downloads (Pure)

Cyanidin Chloride inhibits ovariectomy-induced osteoporosis by suppressing RANKL-mediated osteoclastogenesis and associated signaling pathways

Cheng, J., Zhou, L., Liu, Q., Tickner, J., Tan, Z., Li, X., Liu, M., Lin, X., Wang, T., Pavlos, N. J., Zhao, J. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2502-2512 11 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis

Hong, G., Kuek, V., Shi, J., Zhou, L., Han, X., He, W., Tickner, J., Qiu, H., Wei, Q. & Xu, J., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8526-8537 12 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
205 Downloads (Pure)